血管源性轻度认知障碍中医术语的临床初步验证  

Preliminary clinical verif ication of traditional Chinese medicine terms about vascular mild cognitive impairment

作　　者：张允岭[1] 金香兰[1] 陈志刚[1] 郭蓉娟[1] 侯小兵[1] 陈宝鑫[1] 高芳[1] 白文[2] 戴中[2] 柳洪胜[2] 谢颖桢[3] 王麟鹏[4] 郭静[4] 

机构地区：[1]北京中医药大学东方医院,北京100078 [2]北京大学人民医院,北京100044 [3]北京中医药大学东直门医院,北京100700 [4]首都医科大学附属北京中医医院,北京100010

出　　处：《中华中医药杂志》2009年第3期301-304,共4页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：首都医学发展科研基金联合攻关项目资助(No.SF-2005-3);北京市新医药学科群建设项目资助(No.XK100270569);211工程重点学科建设项目资助;2008年中医药行业科研专项资助(No.200807011)

摘　　要：目的:临床验证血管源性轻度认知障碍核心症状观察表,规范中医术语。方法:设计前瞻性观察方案,收集155例血管源性轻度认知障碍患者,对血管源性轻度认知障碍核心症状观察表,进行信度、效度评定。结果:验证并优化出"言谈不知首尾,时作时止","转盼遗忘","语后便忘,回忆不能","神思不聚","持筹握算差","犹豫不决","言语懒","言语如凝","言善误","兴趣索然","思维迟钝","反应迟钝","忧愁思虑","肢体笨拙","步履迟重"等24项核心症状。结论:24项核心症状能较全面地描述血管源性轻度认知障碍患者的状态,所用术语与痴呆术语有较好的区分,可以运用于病情描述。Objective： To verify and standardize the traditional Chinese medicine （TCM） terms about vascular mild cognitive impairment. Methods： Prospective observation was adopted.155 Leukoaraiosis （LA） with mild cognitive impairment patients were selected to verify the reliability and validity of core symptoms questionnaire of vascular mild cognitive impairment. Results： 24 core symptoms were verified and nominated in traditional Chinese phrases.For example,the English meanings were： when talking one can＇t remember his beginning and often stop; forgetting something soon; after saying out something, one suddenly forget it and can＇t remember; inability to concentrate; bad at calculation; be in two minds; lazy to talk; talk too slowly; low interest in every thing; slow in mind; retarded thinking; retarded reaction; feelings of sadness; physically clumsy; walking slowly and heavily, et al. Conclusion： The 24 terms could describe the clinical features of vascular mild cognitive impairment generally. The terms of vascular mild cognitive impairment were different from those of dementia.

关 键 词：血管源性 轻度认知障碍 中医术语 临床验证 

分 类 号：R277.7[医药卫生—中医学]