肿瘤与肿瘤标志物研究中证据的思考  

About the Evidence of Tumor Marker in Tumor Studies

作　　者：靳晓亮[1] 杨波[1] 关方霞[2] 宋来君[1] 李远[1] 焦红亮[1] 郭亚男[2] 

机构地区：[1]郑州大学第一附属医院神经外科,河南郑州450052 [2]郑州大学生物工程系,河南郑州450001

出　　处：《医学与哲学（B）》2009年第2期48-50,共3页Medicine & Philosophy(B)

基　　金：河南省医学科技创新人才工程项目;项目编号:2006002;河南省医学科技攻关计划项目(重点项目);项目编号:200702003;教育部新世纪优秀人才支持计划;项目编号:2006NCET-01

摘　　要：随着对肿瘤研究的深入,人类发现的肿瘤标志物越来越多。目前有一定临床价值的肿瘤标志物已达100多种,但经过10多年的临床实践发现,肿瘤与其标志物之间的关系错综复杂。现有的许多研究中实验设计以及对结果的分析都存在着一些问题,得出的结论缺乏直接或确凿的证据,甚至出现偏差的结论,以致于影响到临床的准确应用。所以,有必要对此进行总结和探讨,以期有效发挥肿瘤标志物的临床应用价值。As the processing of profound studies on tumor, more and more tumor markers were found. Currently, there have been more than 100 kinds of tumor marker showing clinical value. However, after 10 years＇ clinical practice, the relationship between tumor and tumor marker is getting more complicated. There are some problems such as the experiment design, the analysis of the result, the reached conclusion lacking direct evidence or even misleading. All these deviation will hinder the accurate clinical application. So, it is necessary to summarize and think over in order to make the tumor marker more valuable in clinic.

关 键 词：肿瘤 肿瘤标志物 证据 

分 类 号：R730.43[医药卫生—肿瘤]