神经干细胞工程化的研究进展  

Progress in neural stem cell engineering

作　　者：魏雁[1] 陈刚[2] 

机构地区：[1]新疆医科大学研究生院,新疆维吾尔自治区乌鲁木齐市830054 [2]新疆维吾尔自治区人民医院神经外科,新疆维吾尔自治区乌鲁木齐市830001

出　　处：《中国组织工程研究与临床康复》2009年第6期1159-1162,共4页Journal of Clinical Rehabilitative Tissue Engineering Research

基　　金：GFP标记的神经干细胞移植治疗脑瘫;新疆维吾尔自治区科技攻关和重点科技课题资助项目(200633128(2))~~

摘　　要：神经干细胞具有自我更新能力和多分化潜能,随着神经干细胞分离培养技术日渐成熟和深入,许多研究者对神经干细胞进行人工改造,产生了工程化的神经干细胞,如可示踪的神经干细胞、有治疗基因的神经干细胞、把神经干细胞改造成永生化的神经干细胞。文章对神经干细胞的基本特性及近年来神经干细胞工程化的研究进展做一综述。Neural stem cells have many characteristics of high self-renewal and multipotentiality. With the maturity and development of separation and incubation technique of neural stem cells, many researchers have studied neural stem cells and produced engineered neural stem cells, such as neural stem cells with labeled ability, therapeutic gene and immortalization. This article is to summarize the basic characteristics of neural stem cells and the present studies on engineering of neural stem ceils.

关 键 词：神经干细胞 工程化 基因治疗 

分 类 号：R394.2[医药卫生—医学遗传学]