Leptin基因多态性与欧拉型藏羊体重性状相关性研究  

Research for Association between Ola Tibet Sheep Leptin Genetic Marker and Carcass Econ Traits

作　　者：刘众[1] 王小龙[1] 马蕊霞[1] 何革新[1] 薛鹏[1] 陈玉林[1] 

机构地区：[1]西北农林科技大学动物科技学院,陕西杨凌712100

出　　处：《西北农业学报》2009年第1期14-19,共6页Acta Agriculturae Boreali-occidentalis Sinica

基　　金：农业部结构调整重大技术研究专题"肉羊快速繁育及高效舍饲养殖关键技术研究与规范"(05-07-03B)

摘　　要：采用PCR-SSCP技术研究了欧拉型藏羊Leptin基因的多态性。在考虑不同位点存在交互作用的前提下,利用数量遗传统计学,从宏观角度分析了4个多态位点各自基因型以及各位点不同基因型组合的最小二乘均值(LSM)、最小二乘效应值(LSE)及其遗传方差,通过标记位点与经济性状的遗传相关预测了选择反应。结果表明,体重性状上L3-BB基因型的LSM最高;L1-AA与L4-AB组合的交互效应LSM仅次于L3位点。说明L3-BB基因型可作为首选标记基因型,L1-AA与L4-AB组合可作为辅助标记基因型组合。To evaluate the effects of polymorphism of the candidate gene-leptin in Ola Tibet sheep. The DNA molecular marker technologies PCR-SSCP were applied. The association between the four polymorphisms loci and the carcass traits were analyzed using general linear model （GLM）, least squares estimation （LSE） and genetic variance. The selection response of the gene was also evaluated. Showed that in the the body weight, the LSM of the genotype of LB-BB was the highest; the interaction effect of combination of L1AA and the L4-AB genotype was lower than that of LB. The genotype of La-BB was can be used as a molecular marker, and the combination of L1AA and the L4-AB can be used as a supplementary marker.

关 键 词：欧拉型藏羊 LEPTIN 遗传方差分析 交互作用 

分 类 号：S826.92[农业科学—畜牧学]