云南高校图书馆联盟文献共享服务平台- LEPTIN

LEPTIN: 作品数：1013被引量：3282H指数：20; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：赵茹茜颜光涛林季王录焕薛辉更多>>; 相关机构：南京农业大学西北农林科技大学中国人民解放军总医院华中农业大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划国家科技支撑计划国家高技术研究发展计划更多>>

Novel perspectives on leptin in osteoarthritis:Focus on aging: 《Genes & Diseases》2024年第6期237-257,共21页Zimo Liu Wenqing Xie Hengzhen Li Xu Liu Yao Lu Bangbao Lu Zhenhan Deng Yusheng Li; supported by the National Key R&D Program of China (No.2019YFA0111900);the National Natural Science Foundation of China (No.81874030,82072506);the National Clinical Research Center for Geriatric Disorders (China) (No.2021LNJJ05);the Provincial Key R&D Program of Hunan,China (No.2020SK2075);the Administration of Traditional Chinese Medicine of Hunan Province,China (No.2021075);the Innovation-Driven Project of Central South University (China) (No.2020CX045);Hunan Yong Talents of Science and Technology (China) (No.2021RC3025);Wu Jieping Medical Foundation (No.320.6750.2020-03-14);the Independent Exploration,Innovation Project for Postgraduate Students of Central South University (China) (No.2021zzts1024);the Hunan Provincial Innovation Foundation for Postgraduate (China) (No.CX20210360);Guangdong Basic and Applied Basic Research Foundation (China) (No.2021A1515220030).; t Osteoarthritis(OA)is a common chronic joint disease characterized by articular cartilage degeneration,subchondral sclerosis,synovitis,and osteophyte formation.OA is asso-ciated with disability and impaired quality o...; 关键词：AGING Articular chondrocytes Cellular senescence DEGENERATION LEPTIN OSTEOARTHRITIS

A single session of strength training changed plasma levels of resistin,but not leptin in overweight and obese men: 《Sports Medicine and Health Science》2024年第4期324-330,共7页Yago Martins Fortes Antonio Felipe Souza-Gomes Alessandro Roberto Silveira Moreira Leo Nogueira Campos Samara Silva de Moura Lucelia Scarabeli Silva Barroso Marcelo Henrique Salviano de Faria Heliana de Barros Fernandes Aline Silva de Miranda Hugo Cesar Martins-Costa Ana Cristina Simoes e Silva Janaina Matos Moreira Albena Nunes-Silva; Obesity has a complex multifactorial etiology and is characterized by excessive accumulation of adipose tissue.Visceral adipose tissue has deleterious effects on health because it secretes large amounts of inflammator...; 关键词：Strength training Adipose tissue Obesity Chronicinflammation RESISTIN LEPTIN

Survivin reduces leptin expression level and improves leptin sensitivity in obese mice: 《China Medical Abstracts(Internal Medicine)》2024年第4期211-211,共1页MIRIAYI Alimujiang; Objective To investigate the role of survivin in the regulation of leptin expression and its sensitivity.Methods Survivin was overexpressed in adipocytes via lentivirus,and the RNA-sequencing(RNA-seq)was used to explo...; 关键词：injection SURVIVIN TARGETED

Insights into the anorexic mechanism of Khat:an integrated in vivo,ex vivo,and in silico investigations: 《Traditional Medicine Research》2024年第10期36-51,共16页Ahmed Ali Jerah Manal Mohamed Elhassan Taha Abdullah Farasani Sivakumar Sivagurunathan Moni Emad Sayed Shaheen Andleeb Khan Ibrahim Abdo Khardali Magbool Oraiby Heyam Mohamed Ali Sidahmed Siddig Ibrahim Abdelwahab; The authors extend their appreciation to the Deputyship for Research&Innovation,Ministry of Education in Saudi Arabia,for funding this research work through project number ISP23-82.; Background:Chewing Khat(Catha edulis)releases cathine and cathinone,which may reduce appetite via an unknown mechanism.This study investigated the peripheral and central effects of fresh leaves and buds of Catha eduli...; 关键词：Catha edulis APPETITE LEPTIN GHRELIN 5-HYDROXYTRYPTAMINE molecular docking

Leptin Modulates the Differentiation of Keratinocytes via Autophagy in Psoriasis Patients With Metabolic Syndrome: 《International Journal of Dermatology and Venereology》2024年第3期121-130,共10页Cui-Hao Song Rui Wang Zhen-Kai Zhao Yuan Zhang Jie Sun Xu Zhang Xiang-Yu Ding Jia Bai Xiao-Qiang Liang Xuan-Jin Wei Xiao-Ling Liu Tao Yang Xin-Lin Liang Cheng-Xin Li Bi-Wen Lin; supported by Beijing Natural Science Foundation(No.7212097).; Objective:Psoriasis is associated with a high prevalence of metabolic syndrome(MS),and patients with concomitant psoriasis and MS are more severely affected and less responsive to treatment.However,the molecular mecha...; 关键词：PSORIASIS metabolic syndrome LEPTIN AUTOPHAGY keratinocyte differentiation signal pathway PI3K/AKT/mTOR

血清FGFR2、Leptin对特发性矮小症患儿的诊断价值及其水平与骨代谢指标的相关性: 《检验医学与临床》2024年第16期2357-2361,共5页李丽欣付智伟赵胜侠; 河北省卫生健康委员会指导性科技计划项目(20221656)。; 目的探讨血清成纤维生长因子受体2(FGFR2)、瘦素(Leptin)水平与特发性矮小症患儿骨代谢指标的相关性及其对疾病的诊断价值。方法选取2021年9月至2023年9月于该院就诊的138例特发性矮小症患儿为观察组,另选取同期于该院进行健康体检的14...; 关键词：特发性矮小症儿童成纤维生长因子受体2 瘦素骨代谢指标诊断

Leptin-mediated suppression of lipoprotein lipase cleavage enhances lipid uptake and facilitates lymph node metastasis in gastric cancer: 《Cancer Communications》2024年第8期855-878,共24页Jian Xiao Shuqing Cao Jiawei Wang Pengyu Li Quan Cheng Xinyi Zhou Jiacheng Dong Yuan Li Xinyu Zhao Zekuan Xu Li Yang; National Natural Science Foundation of China,Grant/Award Number:81874219;Jiangsu Province Capability Improvement Project through Science,Technology,and Education,Grant/Award Number:ZDXK202222。; Background:Lymph node metastasis(LNM)is the primary mode of metastasis in gastric cancer(GC).However,the precise mechanisms underlying this process remain elusive.Tumor cells necessitate lipid metabolic reprogramming ...; 关键词：angiopoietin-like protein 4 LEPTIN lipoprotein lipase lymph node metastasis prostaglandin E2

TET2:the fat controller of leptin: 《Life Metabolism》2024年第4期52-54,共3页Callen C.Goldsmith Garron T.Dodd; The mechanisms underlying leptin resistance in obesity remain incompletely understood.A recent publication in Nature Communications by Zeng et al.reports a previously undefined negative feedback loop involving ten-ele...; 关键词：TET2 OBESITY

右归丸调节Leptin/JAK2/STAT3信号通路抑制肾阳虚COPD大鼠气道炎症被引量：3: 《中国实验方剂学杂志》2024年第14期17-26,共10页郑岚罗泽源萧闵江晓翠孟宇豪陈思易周晶; 国家自然科学基金青年项目(82104825)。; 目的:观察右归丸对肾阳虚慢性阻塞性肺疾病(COPD)大鼠肺组织瘦素(Leptin)/酪氨酸激酶2(JAK2)/信号转导与转录激活因子3(STAT3)信号通路的影响。方法:采用第1、14天时气管滴注脂多糖,并连续烟熏6周,期间隔3 d肌注氢化可的松,复制40只肾阳...; 关键词：慢性阻塞性肺疾病(COPD) 右归丸白细胞介素-17A(IL-17A) 瘦素酪氨酸激酶2/重组人信号转导与转录激活因子3

瘦素及其受体在牦牛附睾的时空表达特性: 《农业生物技术学报》2024年第2期334-343,共10页王晓艳崔燕余四九马睿何俊峰张虔龙敏; 国家自然科学基金(31972634)。; 瘦素(leptin)及瘦素受体(leptin receptor,LEPR)在雄性动物生殖调控中发挥重要作用。为探究Leptin及LEPR在性成熟前后牦牛(Bos grunniens)附睾头、体、尾中的分布特点及表达动态,本研究采集性成熟前(幼年)及性成熟后(成年,老年)牦牛附...; 关键词：牦牛附睾瘦素(leptin) 瘦素受体(LEPR)

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