帕金森病伴疼痛临床特征分析  

Clinical analysis on pain in patients with Parkinson's disease.

作　　者：张紫娟[1] 彭蓉[1] 安星凯[1] 毛雪晔[1] 

机构地区：[1]四川大学华西医院神经内科,成都610041

出　　处：《中国实用内科杂志》2009年第3期246-248,共3页Chinese Journal of Practical Internal Medicine

摘　　要：目的探讨帕金森病(PD)患者与疼痛的关系及其临床意义。方法收集2007年5月至2008年2月四川大学华西医院神经内科门诊就诊的162例PD患者的临床资料,选择同期135名年龄、性别与之相匹配的健康成人作对照。分别采用简易疼痛问卷进行评价,并按性别、年龄、起病形式、发病年龄、病程、Hoehn-Yahr(统一帕金森评定量表,H-Y)分级进行统计学分析。结果PD患者疼痛发生率(53.1%)高于对照组(23.7%),差异有统计学意义(P<0.01);PD组及对照组女性疼痛发生率均高于同组男性,差异有统计学意义(P<0.01);随着H-Y分级的增加,PD患者的疼痛程度加重。结论PD患者存在明显的疼痛情况,并且随着疾病的进展而加重。Objective To detect the pain condition in patients with Parkinson＇s disease（PD） and explore the clinical significance. Methods From May 2007 to February 2008, pain was examined in 162 PD patients in Department of Neurology,West China Hospital,Sichuan University and in 135 healthy controls well matched for gender,age and education. Statistics analysis was employed according to gender, age, the form of morbility, early-onset PD or late-onset PD, duration and Hoehn-Yahr degree. Results The incidence of pain in PD patients （53.1% ）was higher than that in the healthy controls （ 23.7% ） （ P 〈 0. 01 ）. The incidence of pain in female with PD and healthy controls was higher than that in male of the same groupe（ P 〈 0. 01 ）. When the Hoehn-Yahr degree increased,the level of pain increased. Conclusion Pain existed significantly in PD patients and developed with the increasing of Hoehn-Yahr degree.

关 键 词：帕金森病 疼痛 

分 类 号：R5[医药卫生—内科学]