锁阳提取物对衰老小鼠抗氧化作用的比较  

Compare antioxidation of different abstracts of Cynomorium songaricum Rupr. in the aging rats

作　　者：刘肇宁[1] 贾海鹰[1] 马丽杰[1] 刘腾[1] 杨丽丽[1] 李兰城[1] 谢军[1] 

机构地区：[1]内蒙古医学院

出　　处：《中国民族医药杂志》2009年第2期42-43,共2页Journal of Medicine and Pharmacy of Chinese Minorities

基　　金：内蒙古医学院青年基金课题(NY2005QN009)

摘　　要：目的：研究锁阳的不同提取液对D-半乳糖致衰小鼠机体的影响。方法：建立小鼠衰老模型，以锁阳的不同提取液给药8周，取血并测定其过氧化氢酶（CAT）、总抗氧化能力、谷胱甘肽过氧化物酶（GSH—PX）三项指标。结果：不同的提取物能明显降低小鼠机体的氧化程度。尤其锁阳醇提物的三项指标，与空白对照组相比无显著性差异，而与D-半乳糖致衰小鼠相比则具有显著性差异。结论：锁阳不同提取物均具有较明显的抗氧化及抗衰老能力，其中醇提物作用最显著。Objective： To Compare antioxidation of different abstracts Cynomorium songaricum Rupr. in the D - gal - induced aging rots.Methods： D - gal - induced aging rats are fed on different abstracts of Cynomorium songaricum Rupr. Daily. After 8 weeks, the activities of CAT, total antioxidation, and GSH - PX in blood were determined. Results： Compared with aging group, the activities of CAT, total antioxidation, and GSH - PX in rats fed on abstracts of Cynomorium songarieum Rupr. Increased evidently, especially the ethanol abstract increased significantly. Conclusion： the ethanol abstract of Cynomorium songaricum Rupr. has significantly abilities of antioxidation and retarding aging process.

关 键 词：锁阳 抗氧化 儿茶素 

分 类 号：R291.2[医药卫生—民族医学]