Gastroparesis: Current diagnostic challenges and management considerations  

作　　者：Shamaila Waseem Baharak Moshiree Peter V Draganov 

机构地区：[1]Department of Pediatric Gastroenterology, Hepatology and Nutrition, University of Florida,Gainesville, Florida 32610, United States [2]Department of Gastroenterology, Hepatology and Nutrition, University of Florida,Gainesville, Florida 32610, United States

出　　处：《World Journal of Gastroenterology》2009年第1期25-37,共13页世界胃肠病学杂志（英文版）

摘　　要：Gastroparesis refers to abnormal gastric motility characterized by delayed gastric emptying in the absence of mechanical obstruction. The most common etiologies include diabetes, post-surgical and idiopathic. The most common symptoms are nausea, vomiting and epigastric pain. Gastroparesis is estimated to affect 4% of the population and symptomatology may range from little effect on daily activity to severe disability and frequent hospitalizations. The gold standard of diagnosis is solid meal gastric scintigraphy. Treatment is multimodal and includes dietary modification, prokinetic and anti-emetic medications, and surgical interventions. New advances in drug therapy, and gastric electrical stimulation techniques have been introduced and might provide new hope to patients with refractory gastroparesis. In this comprehensive review, we discuss gastroparesis with emphasis on the latest developments; from the perspective of the practicing clinician.Gastroparesis refers to abnormal gastric motility characterized by delayed gastric emptying in the absence of mechanical obstruction. The most common etiologies include diabetes, post-surgical and idiopathic. The most common symptoms are nausea, vomiting and epigastric pain. Gastroparesis is estimated to affect 4% of the population and symptomatology may range from little effect on daily activity to severe disability and frequent hospitalizations. The gold standard of diagnosis is solid meal gastric scintigraphy. Treatment is multimodal and includes dietary modification, prokinetic and anti-emetic medications, and surgical interventions. New advances in drug therapy, and gastric electrical stimulation techniques have been introduced and might provide new hope to patients with refractory gastroparesis. In this comprehensive review, we discuss gastroparesis with emphasis on the latest developments; from the perspective of the practicing clinician.

关 键 词：Gastroparesis  Nausea VOMITING PROKINETIC Therapy 

分 类 号：R573[医药卫生—消化系统]