原发性反流性食管炎临床特征分析  

The study of clinical feature in 553 patients with primary reflux esophagitis

作　　者：郑芳芳[1] 许树长[1] 陈莹[1] 王琛[1] 张霞[1] 

机构地区：[1]同济大学附属同济医院消化内科,上海200065

出　　处：《同济大学学报（医学版）》2009年第1期104-107,共4页Journal of Tongji University(Medical Science)

摘　　要：目的探讨原发性反流性食管炎(reflux esophagitis,RE)患者的基本临床特征及与幽门螺杆菌(Helicobacter pylori,Hp)感染的关系。方法回顾性分析553例经胃镜证实为RE患者的基本临床特征,包括年龄、性别、及Hp感染情况,并进行比较分析。结果由于各种原因2007年7月—2008年7月至我院行胃镜检查的人数为12 354例,RE的检出率为4.47%。检出的RE患者A、B级的占97.47%(539/553),C、D级的占2.53%(14/553)。反流性食管炎的程度与性别无统计学关联(P>0.05)。中年组原发性RE患者最多。RE患者的Hp感染率为50.6%。食管炎程度与Hp菌是否感染无明显统计学关联(P>0.05)。结论轻度RE患者明显较多,RE炎症程度与Hp菌是否感染无明显关系。Objective To study the fundamental clinical feature in patients with primary reflux esophagitis and the relationship between the inflammatory degree and Helicobacter pylori. Methods 553 patients with reflux esophagitis diagnosed by endoscopy were enrolled in the study. The clinical feature was analyzed. The contrast analysis referred to some directions such as age, gender, Helicobacter pylori. Results The number of patients in the corresponding time period who underwent endoscopy was 12 354. The detectable rate of RE was 4.47%. The rate of grade A and B was 97.47% （539/553）, while that of grade C and D was 2.53% （14/553）. There was no statistical association between the level of esophagitis and gender （ P 〉 0.05 ）. The number of middle-aged primary reflux esophagitis was maximum. The detectable rate of Hp in RE patients was 50.6%. No significant correlation was gained between the degree of reflux esophagitis and Hp （ P 〉 0.05 ）. Conclusion Obviously, the degree of so much RE patients is mild. There may be no relationship between RE and Helicobacter pylori.

关 键 词：反流性食管炎 幽门螺杆菌 内镜 

分 类 号：R571[医药卫生—消化系统]