迟发性皮肤类脂蛋白沉积症  

Cutaneous lipoid proteinosis:a case in old age

作　　者：毛玉洁[1] 陈明华[1] 陈连军[1] 秦海红[2] 吴文育[1] 

机构地区：[1]复旦大学附属华山医院皮肤科,上海200040 [2]上海市第九人民医院周浦分院皮肤科,上海201318

出　　处：《临床皮肤科杂志》2009年第3期168-170,共3页Journal of Clinical Dermatology

摘　　要：报告1例迟发性皮肤类脂蛋白沉积症。患者男,67岁。双下肢出现皮损4年,面部、手部皮损3年余。眼睑处皮损为象牙至淡黄色串珠状排列的丘疹,双手疣状丘疹及双下肢鱼鳞病样损害,结合组织病理检查PAS染色有阳性物质沉积,诊断为类脂蛋白沉积症。该例患者发病年龄大,组织病理检查真皮内较多中性粒细胞浸润,以往文献中无类似报道,尚需进一步随访。One ease of cutaneous lipoid proteinosis is reported. A 67-year-old man presented with a 4-year history of skin eruptions on the lower extremities and a more than 3-year history of skin lesions on the face and hands. Physical examination revealed ivory white to light yellow, beaded, linear lesions on the palpebrae, verrueiform papules on the hands, and iehthyosis- like lesions on the lower extremities. The ease was diagnosed as lipoid proteinosis, according to the clinical manifestations and the histopathologieal findings, espoeially positive PAS staining. However, the onset in old age and the dermal infiltration of neu- trophils of this ease were quite different from the typical eases of lipoid proteinosis, the patients needs to be followed up.

关 键 词：类脂蛋白沉积症 迟发性 

分 类 号：R758.4[医药卫生—皮肤病学与性病学]