直、乙状结肠海绵状血管瘤7例临床病理分析  

Clinicopathological features of diffuse cavernous hemangioma in rectosigmoid colon

作　　者：陈铜兵[1] 何妙侠[2] 吴晓辉[2] 朱明华[2] 

机构地区：[1]江苏省常州市第一人民医院病理科,常州213000 [2]第二军医大学长海医院病理科,上海200433

出　　处：《临床与实验病理学杂志》2009年第1期69-71,共3页Chinese Journal of Clinical and Experimental Pathology

摘　　要：目的探讨7例直、乙状结肠海绵状血管瘤临床与病理学特征,诊断与鉴别诊断,以及治疗原则与疗效。方法回顾2000～2007年诊治的7例直、乙状结肠海绵状血管瘤临床与病理资料。结果7例直、乙状结肠海绵状血管瘤平均年龄31.5岁,男性6例,女性1例,均以间歇性便血就诊,所有病例均接受手术切除治疗。肿瘤切面暗红色,蜂窝状,镜下由大小不一的薄壁血管构成;免疫组化CD34+、CD31+、SMA-、FⅧRAg、vimentin+、cytokeratin-。术后随访6个月至6年无复发。结论直、乙状结肠海绵状血管瘤较少见,主要症状是便血,早期容易误诊,一旦确诊,宜手术切除治疗,预后良好。Purpose To explore the clinicopathological feature, differential diagnosis and treatment of diffuse cavernous hemangioma in rectosigmoid colon region. Methods Seven eases of rectosigmoid colon diffuse cavernous hemangiomas were studied from 2000 to 2007. Results There were 6 males and 1 female with the median age of 31.5 years in the 7 cases. All patients had painless interval anal bleeding and treatment of operation. The cut surface of tumor was dark-red like and honeycomb, and microscopically, the tumor tissue was made of blood vessels with various size and thickness. Immunohistoehemistry showed the tumor tissue was positive for CD34, CD31, FVIHRAg, SMA and vimentin, and negative for eytokeratin. Follow-up was done in 6 eases from 6 months to 6 years without further anal bleeding. Conclusions Diffuse cavernous hemangioma of reetosigmoid colon is rare. The main complain is interval anal bleeding and the tumor is easily misdiagnosed. Operation is the effective treatment of this tumor and its prognosis is better.

关 键 词：直 乙状结肠肿瘤 海绵状血管瘤 临床病理诊断 治疗 

分 类 号：R735.34[医药卫生—肿瘤]