口腔修复非贵金属材料对L-929细胞毒性的研究  

Toxicity of Non-precious Dental Materials on the L-929 Cell

作　　者：浦美泓[1] 罗晓晋[1] 

机构地区：[1]山西医科大学口腔医学系,山西太原030001

出　　处：《口腔医学研究》2009年第1期51-54,共4页Journal of Oral Science Research

摘　　要：目的:评价5种口腔修复非贵金属材料的细胞毒性。方法:采用细胞培养法、MTT法和流式细胞仪检测细胞周期的方法,研究5种合金的细胞毒性。结果:MTT比色法结果揭示:纯钛、钛合金具有良好生物相容性,而钴铬合金、镍铬合金、铜基合金抑制了细胞的生长。细胞周期所测各组细胞G2期比例与MTT结果相符。结论:不同金属合金的细胞毒性不同。Objective： To 5 evaluate the biocompatibility of non -precious dental metals. Methods： We used cell culture, MTT and flow cytometry was to study the biocompatibility of five metal alloys. Results： MTT eolorimetrie assay suggested ： copper alloy was cytotoxic 3, nickel chromium alloy group of cells for the attainment of level 2, cobalt - chromium alloy group for a cell toxicity, and other groups for the cytotoxic 0. The cell cycle measured in each group for the G2 cells, the proportion from low to high ranking with MTT results. Conclusion： Different metal alloys have different cell toxicity.

关 键 词：细胞毒性 细胞周期 

分 类 号：R783.1[医药卫生—口腔医学]