保留肾单位手术治疗肾癌14例临床分析  

Clinical analysis of nephron-sparing surgery for renal cell carcinoma in 14 cases

作　　者：郑杰[1] 杨全成[1] 贾东升[1] 郑建波[1] 

机构地区：[1]淄博市中心医院泌尿外科,山东淄博255036

出　　处：《现代肿瘤医学》2009年第3期528-530,共3页Journal of Modern Oncology

摘　　要：目的:探讨保留肾单位手术治疗肾癌的安全性和疗效。方法:回顾性分析1996年6月至2007年6月间14例行肾单位保留手术的肾癌患者的临床资料,其中双侧肾癌1例,孤立肾肾癌2例,对侧肾有病变或潜在功能损害的肾癌4例,对侧肾正常的肾癌7例。肿瘤直径1.6cm-6.8cm,平均4.2cm。14例中行肿瘤剜除术3例,行肾部分切除术6例,肾楔形切除术5例。结果:14例患者手术均成功。术后随访9-88个月,平均40个月,1例出现远处转移死亡(双侧肾癌患者),1例患者于术后12个月局部复发改行根治性肾切除术,2例术后出现暂时性肾功能不全。结论:保留肾单位手术治疗肾癌安全有效,尤其适用于低分期小肾癌患者。Objective：To investigate the safety and effect of nephron-sparing surgery in treatment of renal cell carcinoma.Methods： A total of 14 cases with renal cell carcinoma underwent nephron-sparing surgery from June 1996 to June 2007.The clinical data and follow-up results were analyzed retrospectively.Of 14 cases,there was 1 patient with bilateral tumors,2 patients with solitary kidney tumors.The contralateral kidney function were damaged in 4 cases,while function-well contralateral kidney existed in other 7 cases.The tumor diameter ranged from 1.6 to 6.8 cm with a mean of 4.2 cm.3 patients underwent enucleation,6 patients underwent partial nephrectomy and 5 patients were performed wedge resection.Results： The operation was performed successfully in all the 14 cases.The postoperative fullow-up ranged from 9 to 88 months with a mean of 40 months.The bilateral-tumor patient died of distant metastasis and 1 case underwent radical nephrectomy because of local recurrence 12 months after operation.Transient renal inadequacy happened in 2 cases.Conclusion： Nephron-sparing surgery is safe and effective for the treatment of renal cell carcinoma and especially indicated for patients with a small,localized low-stage renal tumor.

关 键 词：肾肿瘤 癌 保留肾单位手术 

分 类 号：R737.11[医药卫生—肿瘤]