甘露醇在脑血管病患者中的应用  

Application of Mannitol in Patients with Cerebrovascular Diseases

作　　者：杜正强[1] 王鸿雁[1] 王平[1] 邢成名[1] 

机构地区：[1]中国海洋大学附属青岛市市立医院神经内科,青岛266071

出　　处：《中华脑血管病杂志（电子版）》2008年第6期349-353,共5页Chinese Journal of Cerebrovascular Diseases(Electronic Edition)

摘　　要：甘露醇一直作为治疗脑水肿和降低颅内压的常规药物,但目前临床疗效争议较大,而且缺乏循证医学证据。文章就甘露醇的药理学作用、脱水降颅压的作用机制及其在缺血性和出血性脑血管病患者中的临床应用做了综述。Mannitol has been used as a convemional drug in the treatment of cerebral edema and reducing intracranial pressure, but its clinical efficacy has been more controversial, and lack of evidence of evidence-based medicine. This article reviews the pharmacological effect of mannitol, mechanism of reducing intracranial pressure by cerebral dehydration and its clinical application in patients with ischemic and hemorrhagic cerebrovascular diseases.

关 键 词：甘露醇 脑血管病 患者 临床应用 疗效 

分 类 号：R743.3[医药卫生—神经病学与精神病学]