喉癌术后复发因素Cox模型评价  

Evaluation of Factors Causing Laryngeal Cancer Recurring Postoperatively with Cox Model

作　　者：吉晓滨[1] 梁赐芳[1] 

机构地区：[1]广州市第一人民医院耳鼻咽喉科,510180

出　　处：《广东医学》1998年第4期253-259,共7页Guangdong Medical Journal

摘　　要：对295例喉癌手术患者随访3年以上，确诊复发31例。对造成复发的可能因素进行Cox模型分析，显示T分期、N分期、肿瘤溃疡、发生声门上区、发生声门下区五项是引起复发的主要因素；肿瘤间质淋巴细胞浸润为防止复发的保护因素。依此结果建立复发多因素模型目标方程和危险指数方程。这些结果为临床判断喉病术后复发倾向提供了参考。295 patients with laryngeal cancer were observed for 3 years postoperatively ,31 cases recurrence were diag-nosed. The foctors possibly causing recurrence were analyzed with Cox model. Resulte were as follows: Such factors as primarytumor's T grade , Cervical lymph metastatic node's N grade, tumor ulcer, origination or expanding in supraglottic arca, origi-naion or expanding in infraglottic area are main ones which can cause neoplasm recurring. Invation of lymphocyte in tumor inter-stitium is protecting factor which prevents neoplasm recurring. By these results, recurring multifactorial model objective equationand hazard index equation were founded. These findings were of benefit to calculate the tendency of laryngeal neoplasm recurringpostoperatively, and should be attach importance to in evaluating subsistence.

关 键 词：喉肿瘤 外科手术 复发 COX模型 

分 类 号：R739.650.5[医药卫生—肿瘤]