不同年龄段短暂性脑缺血发作患者选择注意功能的病例对照研究  

Paired case-control study of the selective attention function of transient ischemic attack patients with different ages

作　　者：陈旭[1] 宋云[2] 唐茂芹[1] 

机构地区：[1]山东省精神卫生中心山东大学医学院,山东济南250014 [2]山东大学附属千佛山医院

出　　处：《中国老年学杂志》2009年第5期567-569,共3页Chinese Journal of Gerontology

摘　　要：目的探讨不同年龄段短暂性脑缺血发作(TIA)患者的选择注意功能状况及药物治疗对其影响。方法选取91例患者,并按同龄、同性别与91例正常人组成配对,使用Stroop色词测试指标评估正常对照组、病例组治疗前和治疗后的选择注意功能。结果病例组与对照组相比,其卡片C耗时、错误率等指标较对照差(P<0.01);病例组内比较发现,老年组较非老年组耗时、Stroop干扰效应(SIE)错误数多(P<0.05)。经尼莫地平、阿司匹林和银杏叶片治疗后,非老年组SIE错误数较治疗前有改善,与非老年组无显著差异;老年组仅卡片C耗时有改善,与非老年组无显著差异。结论TIA患者存在选择注意功能障碍,同时其有一定可塑性,不同年龄段患者的药物治疗效果有所不同。Objective To explore the correlation of selective attention function among transient ischemic attack （TIA） patients with their age groups and use of different medications. Methods 91 TIA patients were selected and were paired with another 91 normal persons against age and gender. Stroop color-word tests were applied to evaluate the selective attention function of patients before and after their use of medications, as well as the cases in the normal group. Results Compared with the control group, patients had longer reaction time and more error counts of Card C （P 〈 0. 01 ）. Patients of old age group had long reaction time and more error counts of Stroop interference effect （SIE） than patients of young age group （P 〈0. 05）. After treatment of nimodipine, aspirin and gingko leaf tablets, patients of young age group reduced their reaction time and error accounts （ P 〈 0. 05 ）. However, patients of old age group only improved their reaction time of Card C （ P 〈 0.05 ）. Conclusions The selective attention impairment of TIA patients can be improved through medications. However, the effects are different among patients with different age groups.

关 键 词：短暂性脑缺血发作 Stroop色词测试 选择注意功能 

分 类 号：R743.31[医药卫生—神经病学与精神病学]