急性脑梗死与超敏C反应蛋白相关性研究  

The Relationship between Highly Sensitive C Reactive Protein and Acute Cerebral Infarction

作　　者：赵丽[1] 林晓东[1] 王学敏[1] 王海英[1] 田小卫[1] 李福学[1] 

机构地区：[1]河北省秦皇岛市第二医院,河北秦皇岛066600

出　　处：《中国现代医生》2009年第8期11-12,共2页China Modern Doctor

基　　金：秦皇岛市科学技术研究与发展计划项目(项目编号:2008-20)

摘　　要：目的探讨急性脑梗死患者血清超敏C-反应蛋白(hs-CRP)水平的变化及其与脑梗死部位、严重程度及预后的关系。方法测定120例急性脑梗死患者和90名健康人血清hs-CRP的含量,按脑卒中患者临床神经功能缺损程度评分标准对患者进行评分,分组比较。结果脑梗死组血清CRP水平明显高于正常对照组(P<0.01)。不同病变部位的梗死患者血清hs-CRP水平比较无显著性差异。脑梗死轻、中、重型患者血清hs-CRP水平差异有统计学意义(P<0.05)。血清CRP水平越高的脑梗死患者病情越严重,临床预后差。结论血清hs-CRP水平增高与脑梗死的发生和严重程度有密切关系,而与病变部位无关。Objective To investigate the changes of the serum level of highly sensitive C-reactive protein （hs-CRP） in patients with acute cerebral infarction and its relationship to the lesions, severity of cerebral infarction. Methods The serum levels of hs-CRP in 120 patients and 90 healthy persons were determined. All the patients were scored by clinic neurological deficit scale, and compared in groups. Results The serum level of hs-CRP in the patients was significantly higher than that in normal control group（P〈 0.01 ） ,different lesion of infarction erum hs-CRP levels had no difference.It was significantly higher in the serious group than in the middle and mild groups （P 〈 0.05 ）. Conclusion The serum level of hs-CRP is closely correlated with the severity of cerebral infarction and has nothing to do with the lesion.

关 键 词：动脉粥样硬化 脑梗死 C-反应蛋白 病变部位 预后 

分 类 号：R743.3[医药卫生—神经病学与精神病学]