牙本质发生不全Ⅱ型的研究现状  

Research actuality of the dentinogenesis imperfecta type Ⅱ

作　　者：丁农乐[1] 杨正[2] 刘敏[1] 杨四维[2] 

机构地区：[1]泸州医学院附属口腔医院修复科,四川泸州646000 [2]泸州医学院附属口腔医院正畸科,四川泸州646000

出　　处：《国际口腔医学杂志》2009年第2期215-217,共3页International Journal of Stomatology

摘　　要：牙本质发生不全Ⅱ型(DGI-Ⅱ)又名遗传性乳光牙本质,为常染色体显性疾病,表现为牙结构的异常。其发病与牙本质涎磷蛋白的突变有关。下面就DGI-Ⅱ的基因研究、遗传方式、病理改变、临床治疗作一综述。Dentinogenesis imperfecta type Ⅱ （DGI-Ⅱ ）is an autosomal dominant inherited disease. A pathogenesis gene has been located on human chromosome 4q21. At present, the mutations of dentin sialophosphoprotein are one of the reasons of DGI-Ⅱ. This review presented the researches on genetic investigation, inheritance, microscopic anatomy, clinical solutions of dentinogenesis imperfecta type Ⅱ.

关 键 词：牙本质发生不全Ⅱ型 牙本质涎磷蛋白 口腔修复学 

分 类 号：R781.2[医药卫生—口腔医学]