宫颈高度病变临床特点——附132例临床分析  

Clinical characteristics of cervical high-grade lesion

作　　者：赵昀[1] 崔淑慧[1] 任丽华[1] 赵超[1] 魏丽惠[1] 

机构地区：[1]北京大学人民医院妇科,100044

出　　处：《中国妇产科临床杂志》2009年第2期88-90,共3页Chinese Journal of Clinical Obstetrics and Gynecology

基　　金：北京大学医学部"985"二期学科建设项目(985-2-015-24)资助

摘　　要：目的总结宫颈高度病变(CIN2、3)的临床特点,探讨对其筛查诊断的最佳方案。方法对北京大学人民医院门诊2007年2月至10月间132例经病理诊断为宫颈高度病变(CIN2、3)患者的临床特点、细胞学、HR-HPV检测及阴道镜检查结果进行分析与总结。结果132例中有103(78.0%)存在不同程度的临床症状。接触性出血65例(49.2%),阴部瘙痒56例(42.4%),白带量多伴异味者103例(78.0%),同时存在两种以上症状98例(74.2%);宫颈呈中重度"糜烂"者占87例(65.9%)。细胞学报告异常者,即不典型鳞状上皮(ASCUS)以上者127例(96.2%),高危型人乳头瘤病毒(HR-HPV)检查(HC2)阳性118例(89.4%),阴道镜检查满意并拟诊为高度病变(HSIL)99例(75.0%)。结论筛查和诊断宫颈高度病变(CIN2、3)时,需要将多种检查方法相结合进行综合分析,尽量避免漏诊的发生。Objective To summarize the clinical characteristics of cervical high- grade lesion and to discuss the optimal screen method for it. Methods A total of 132 cases of cervical high - grade lesion were analyzed on their cytology test, high risk- HPV test, colposcopy with cervical biopsy. Results In the 132 cases, 103 （78. 0%） cases presented clinical symptoms, including 65 cases （49.2%） with contact hemorrhages, 56 cases （42. 4%） with genitals itch, 103 cases （78.0%） with abnomal vaginal discharge; and 98 cases （74. 2%） were with two or more symptoms; 87 （65.9%） were with cervical erosion, 127 （96.2%） with abnormal cytology, 118 （89.4%） were HR-HPV positive, 99 （75.0%） with satisfactory colposcopy and 99 （75.0%） with colposcopic impression of high-grade lesion. Conclusions Although cervical high- grade lesion presents some common characteristics, each test method has its limitation. Combination of multiple tests is helpful in avoiding missed diagnosis.

关 键 词：宫颈高度病变 细胞学 阴道镜 HPV高危型 

分 类 号：R737.33[医药卫生—肿瘤]