Ge-132对半乳糖性白内障的研究  

A Study Of Germanium-132 on Galacoose Cataracts in Rats

作　　者：陈翠真[1] 董冰[1] 

机构地区：[1]北京市眼科研究所,北京100730

出　　处：《广东微量元素科学》1998年第1期20-22,共3页Trace Elements Science

摘　　要：扼要叙述了Ge－132的性质、结构、生物学特性及临床应用等，重点介绍了Ge－132用于半乳糖性白内障的研究方法、结果和讨论，旨在通过Ge－132抑制与晶体混浊有关的糖基代末端产物（AGEs）形成，逆转糖基化蛋白为溶解状态，抑制或延缓白内障的发生和发展，为老年性或糖尿病性白内障开辟新的治疗途径。This paper gives an outline on Ge-132's properties, structure, biological features, clinical applications, and attached importance to its study methods and results and discusses on the effect of Ge-132 on galactose induced cataractogenesis. It is aimed at inhibitting the formation of advanced glycation and products (AGEs) related to lens opacification by Ge-132, and at reverting glycated proteins into solubilization, which is effective on inhibiting or delaying the formation and the development of galactose-induced cataracts and explores new way for preventing senile or diabetic cataract.

关 键 词：锗132 半乳糖性白内障 有机锗化合物 白内障 

分 类 号：R776.105[医药卫生—眼科] R988.1[医药卫生—临床医学]