人参皂甙Rg3对乳腺癌术后CA153升高的临床疗效探讨  

Clinical efficacy of panaxoside Rg3 on high levels of CA153 in postoperative breast cancer patients

作　　者：周毅[1] 吴池华[1] 胡刚[1] 张涛[1] 

机构地区：[1]四川省人民医院乳腺外科,四川成都610072

出　　处：《实用医院临床杂志》2008年第5期37-38,共2页Practical Journal of Clinical Medicine

摘　　要：目的观察人参皂甙Rg3在乳腺癌术后CA153值升高患者中的疗效。方法乳腺癌术后及化疗后首次查出CA153值升高的患者80例,治疗组40例,口服人参皂甙Rg3(参一胶囊),每次20 mg,早晚饭前30 min服用,连续服用6个月;对照组40例观察;两组患者均每月查CA153值,连续6个月,比较其水平值变化。结果治疗组CA153水平在6个月后明显下降,与治疗前比较差异有显著性意义(P<0.05);对照组CA153水平在6个月后有升高的趋势。结论对于乳腺癌手术后、化疗后CA153值升高的患者,服用人参皂甙Rg3能明显降低CA153水平值,从而可有效预防其复发转移。Objective To observe the efficacy of panaxoside Rg3 （ Shenyi capsule） on elevated levels of CA153 in postoperative breast cancer patients. Methods Eighty patients who had been treated by breast cancer operation or chemotherapy and were found an elevated level of CA153 at first time were randomized into the treatment group （ n = 40） and the control group （ n = 40）. In the treatment group, panaxoside Rg3 （ Shenyi Capsule ） was taken orally, 20mg per time, twice a day and continuously for 6 months. Patients in the control group did not take it. CA153 levels were observed every month for 6 months. Results CA153 values in the treatment group were obviously decreased in comparison with those before operation （ P 〈 0.05 ）. CA153 values in the control group showed an elevated tendency after 6 months. Conclusion Panaxoside Rg3 can obviously lower CA153 values and accordingly effectively prevent the metastasis of mammary cancer after operation, chemotherapy or radiotherapy.

关 键 词：乳腺癌 人参皂甙RG3 CA153 

分 类 号：R737.9[医药卫生—肿瘤]