胃癌组织中生长激素受体的表达  

Expression of Growth Hormone Receptor in Human Gastric Cancer Tissue

作　　者：梁道明[1] 杨蔚[2] 周东[1] 廖庚进[1] 陈嘉勇[1] 

机构地区：[1]昆明医学院第二附属医院急诊外科,昆明650101 [2]云南省第一人民医院普通外科,昆明650000

出　　处：《中国普外基础与临床杂志》2009年第3期208-210,共3页Chinese Journal of Bases and Clinics In General Surgery

基　　金：云南省教育厅科学研究基金资助项目(项目编号:5Y0309C)~~

摘　　要：目的研究生长激素受体(GHR)在人胃癌组织中的表达情况。方法采用免疫组织化学法检测57例胃癌标本及其远端正常组织中GHR的表达。结果胃癌组织中GHR表达阳性率为80.7%(46/57),远断端正常组织中GHR表达阳性率为70.2%(40/57),两者比较差异无统计学意义(P>0.05)。胃癌组织中GHR的表达与肿瘤分化程度、组织学类型、性别和年龄均无关(P>0.05)。结论胃癌组织和远端正常组织中GHR的表达基本一致。Objective To investigate the expression of growth hormone receptor （GHR） in human gastric cancer tissue. Methods The GHR was detected in samples of the human gastric cancer （57 cases） and the distal normal tissues （57 cases） by immunohistoehemistry technique. Results The GHR expression positive rate was 80.7% （46/57） in the human gastric cancer tissues and 70.2% （40/57） in the distal normal tissues. There was no statistic difference between the human gastric cancer tissues and the distal normal tissues （P〉0.05）. There were also no statistic differences among the gastric cancer tissues of different differentiation, different tissue type, different gender and different age ranges （P〉0.05）. Conclusion It is similar that the expression of GHR between the human gastric cancer tissues and the distal normal tissues.

关 键 词：生长激素受体 胃肿瘤 免疫组织化学 

分 类 号：R735.2[医药卫生—肿瘤]