茶多酚对老龄大鼠血脂及体内抗氧化能力的影响  

Effects of Tea Polyphenol on Blood Lipid and Antioxidation in Vivo in Aged Rats

作　　者：沈新南[1] 陆瑞芳[1] 吴岷[1] 

机构地区：[1]上海医科大学营养与食品卫生教研室

出　　处：《中华预防医学杂志》1998年第1期34-36,共3页Chinese Journal of Preventive Medicine

摘　　要：目的研究茶多酚的降血脂及抗氧化能力。方法以老龄ＳＤ大鼠分设对照组、２％和１％茶多酚３组，共饲养６周检测生化指标。结果茶多酚能降低大鼠血清胆固醇含量，提高ＨＤＬ－Ｃ／ＴＣ比值及显著降低血清脂质过氧化物含量，２％茶多酚组大鼠的红细胞超氧化物岐化酶活性显著高于对照组。对缺铁性贫血大鼠进行４周恢复试验，茶多酚组和对照组大鼠的血红蛋白和红细胞游离原卟啉含量差异无显著性。结论提示茶多酚能增强老龄大鼠体内抗氧化能力，实验剂量的茶多酚对铁在机体内的生物利用并无不良影响。Objective To study the ability of tea polyphenol to lowering blood lipid and antioxidation in the aged rats. Methods The SD rats were divided into three groups, i.e., control group and two trial groups fed with 1% and 2% tea polyphenol for six weeks, respectively. Results Tea polyphenol could reduce serum level of lipid peroxide and increase the ratio of high density lipoprotein cholesterol (HDL C) to total cholesterol (TC), and significantly lower serum level of lipid peroxide in rats. Activities of superoxide dismutase in red blood cells of rats fed with 2% tea polyphenol were significantly higher than those in control ones. Conclusion Tea polyphenol can enhance antioxidation in vivo in the aged rats.

关 键 词：脂蛋白 过氧化脂质 动脉粥样硬化 茶多酚 

分 类 号：R543.5[医药卫生—心血管疾病] R977.9[医药卫生—内科学]