运动对p38MAPK的影响  

Effects on Sport of p38MAPK

作　　者：李善华[1] 尹立莉[2] 唐小雄[1] 

机构地区：[1]广西师范大学体育学院,广西桂林541004 [2]沈阳体育学院研究生部,辽宁沈阳110102

出　　处：《沈阳体育学院学报》2009年第1期62-64,共3页Journal of Shenyang Sport University

基　　金：辽宁省教育厅高等学校科学研究项目课题,编号为2004D243

摘　　要：近年来有关运动骨骼肌信号传导的影响成为该领域的研究热点和前沿,国内外的一些研究表明,丝裂原活化蛋白激酶系统(MAPKs)在细胞信号转导中起着很重要的作用,而其中又以p38MAPK的研究较为深入。它通过作用骨骼肌葡萄糖载体蛋白4(GLUT4)而影响骨骼肌对葡萄糖的转运与摄取,并进而对机体的糖代谢起一定的调节作用。但目前有关运动对P38MAPK影响的结果并不一致,现将最新国内外的研究结果进行归纳和总结,以便为今后的研究提供借鉴。Recently the effect of the exercise in signal transduction of skeletal muscle has become the research hotspot and advancing front in the field. At home and abroad some scholars have indicated that mitogen-activated protein kinase system （MAPKs） in cellular signal transduction plays a very important role ,and p38MAPK is the most in-depth research. It influence transport and ustake of skeletal muscle glucose through glucose transporter protein 4 （GLUT4） of skeletal muscle, and thus glucose metabolism of the body regulating the role of certain, but the results which related to the effects of exercise on P38MAPK are not consistent,now the authors carry out the latest research findings of domestic and overseas to sorting, summing up and concluding, in order to provide reference for future research.

关 键 词：MAPK P38MAPK 运动 糖代谢 

分 类 号：G804.21[文化科学—运动人体科学]