功能性便秘患者直肠肛门动力与直肠感觉功能的研究  

Study on colonic dynamics,anorectal motility,rectal sensation in patients with functional constipation

作　　者：王伟[1] 赵洪川[2] 

机构地区：[1]北京协和医学院研究生院,北京100730 [2]中日友好医院消化科,北京100029

出　　处：《中日友好医院学报》2009年第1期9-12,共4页Journal of China-Japan Friendship Hospital

摘　　要：目的:通过对功能性便秘患者进行结肠传输试验、肛门直肠测压、直肠容量刺激,研究其可能的病理生理学机制。方法:收集2007年7月～2008年5月中日友好医院门诊及住院的功能性便秘患者53例,用不透X线标志物测定全结肠和结肠节段通过时间,通过直肠球囊内注入空气,观察直肠容量刺激对初始感觉阈值、最大耐受性的影响。结果:功能性便秘患者结肠通过时间延长,且主要发生在左半结肠区、乙状结肠直肠区,同时存在肛门直肠动力异常。结论:结肠直肠肛门动力紊乱与直肠感觉异常均参与功能性便秘的发生。Objective：To explore the possible pathophysiology of functional constipation with colonic transit test,anorectal manometry,rectal pressure-stimulation,and to assess its variety of manometric abnormalities and visceral perception.Methods：The data collected during July 2007 to May 2008,there were 53 patients,both the inpatients and out-patients meeting the criteria of Roman.Total and segmental colonic transit times and transit index were assessed radiographically using radiopaque markers,simulating the standard anorectal manometry to monitor the anorectal function,rectal visceral perception thresholds were examined after rectal pressure-stimulation.Results：The colonic transit time in functional constipation patients was significantly prolonged,and major in the area of left colon and anorectum.Abnormalities in anorectal motility were also found in these patiants.Conclusion：Abnormal colonic transition,abnormal anorectal motility and abnormal visceral perception may participate the pathogenesis of functional constipation.

关 键 词：功能性便秘 结肠通过时间 肛门直肠动力 肛门直肠测压 

分 类 号：R574.62[医药卫生—消化系统]