乙二胺四乙酸铁钠口服液治疗小儿缺铁性贫血及对血清微量元素的影响  

Effects of NaFeEDTA liquid on the treatment of iron deficiency anemia and the levels of trace elements in serum in children

作　　者：阚淑月[1] 杨建春[1] 于桂兰[1] 王春艳[1] 王秀兰[1] 

机构地区：[1]河北省唐山市妇幼保健院,063000

出　　处：《中国妇幼保健》2009年第6期848-849,共2页Maternal and Child Health Care of China

基　　金：河北省科学技术研究与发展第一批指导计划立项课题〔课题编号:05276413〕

摘　　要：目的:探讨乙二胺四乙酸铁钠(NaFeEDTA)口服液治疗婴幼儿缺铁性贫血的疗效及其对血清微量元素的影响。方法:对101例缺铁性贫血(IDA)患儿给予NaFeEDTA口服液0.5mg·kg-1·d-1,连服8周,治疗前、后分别测定血常规和微量元素,并与正常儿童进行对照。结果:用药8周后93.0%的IDA患儿血红蛋白(Hb)恢复至正常水平(P<0.01);治疗前IDA患儿血清铁、锌、铜均较正常儿童低(P<0.05),治疗8周后血清铁、锌、铜均较治疗前明显升高(P<0.05),血清钙、镁变化不明显。结论:NaFeEDTA口服液治疗婴幼儿IDA临床效果好,可显著升高血清铁、锌、铜水平。Objective ： To explore the effects of NaFeEDTA liquid on the treatment of iron deficiency anemia and the levels of trace elements in serum in children. Methods： 101 children with iron - deficiency anemia were treated with NaFeEDTA liquid for 8 weeks, 0. 5mg·kg^-1·d^-1. The levels of trace elements in serum and routine analysis of blood were detected before and after treatment and compared to healthy children. Results： The recovery rate of hemoglobin was 93 % after treatment （ P 〈 0. 01 ） . Before treatment the levels of serum iron, zinc and copper were lower than those in the healthy children （ P 〈 0. 05 ） . The levels of serum iron, zinc and copper after treatment were significantly higher than those before treatment （ P 〈 0. 05 ） , NaFeEDTA liquid had no effect on serum levels of calcium and magnesium. Conclusion： The effect of NaFeEDTA liquid is prominent, which can increase the levels of serum iron, zinc and copper remarkably.

关 键 词：缺铁性贫血 NAFEEDTA 疗效 微量元素 

分 类 号：R723[医药卫生—儿科]