2-烷基-6-甲氧基-1,4-苯醌的全合成  

Total Synthesis of 2-Alkyl-6-methoxy-1,4-benzoquinones

作　　者：武利强[1] 杨春广[1] 杨利敏[1] 杨丽娟[1] 

机构地区：[1]新乡医学院药学院,新乡453003

出　　处：《有机化学》2009年第3期444-449,共6页Chinese Journal of Organic Chemistry

基　　金：新乡医学院高学历人才科研启动(No.04GXLP05)资助项目

摘　　要：3,5-二甲氧基苯甲醛经格氏、氧化反应制到3,5-二甲氧基苯基烷基酮,然后在微波辐射下经黄鸣龙还原和选择性脱甲基化、Teuber氧化反应制得目标化合物,产率均在50%以上.产物结构经IR,1H NMR,元素分析等进行了表征.2-Alkyl-6-methoxy-1,4-benzoquinones were synthesized from 3,5-dimethoxybenzaldehyde by Grignard and oxidizing reaction to give 3,5-dimethoxyphenylalkylketones, followed by selective demethylation and Huang Minglong reduction under microwave irradiation, and Teuber oxidizing reaction in good yields. All products were characterized by IR, ^1H NMR spectra and elemental analysis.

关 键 词：微波辐射 2-烷基.6-甲氧基-1 4-苯醌 黄鸣龙还原 合成 

分 类 号：TQ244.61[化学工程—有机化工]