50例肺癌患者中西医结合治疗后舌脉象参数的变化  

Changes of tongue and pulse parameters in 50 lung cancer patients treated with integrated traditional Chinese and Western medicine

作　　者：燕海霞[1] 王忆勤[1] 朱惠蓉[2] 赵丽红[3] 林慈斌[1] 龚其淼[1] 刘彭年[1] 

机构地区：[1]上海中医药大学基础医学院,上海201203 [2]上海中医药大学曙光医院肿瘤科,上海201203 [3]上海中医药大学龙华医院肿瘤科,上海200032

出　　处：《中西医结合学报》2009年第3期218-222,共5页Journal of Chinese Integrative Medicine

基　　金：上海高校选拔培养优秀青年教师科研专项基金资助项目(No.SZY05009);上海市重点学科(第3期)建设经费资助项目(No.S30302)

摘　　要：目的:观察肺癌患者经中西医结合治疗后的舌脉象参数变化,探讨舌脉象客观化参数在中西医结合治疗肺癌临床疗效评价中的作用。方法:应用TP-Ⅰ型舌脉象数字化分析仪检测50例肺癌患者关部脉图及舌象图片,观察患者运用益肺抗瘤饮加化疗治疗前及治疗1、2个月后的舌象参数和脉象参数。舌象参数包括润燥指数、厚薄指数、裂纹指数、胖瘦指数、腐腻指数;脉象参数包括功率谱能比1(power spectral ratio 1,PSR1)、PSR2、PSR3、PSR4以及倒谱能比1(cepstrum spectral ratio 1,CSR1)、CSR2、CSR3、CSR4。比较患者治疗前后舌、脉象客观指标的变化。结果:治疗1、2个月后,患者的脉象参数PSR1升高,PSR2降低,与治疗前比较,差异均有统计学意义(P<0.05);治疗2个月后PSR1降低,PSR2升高,与治疗1个月后比较,差异均有统计学意义(P<0.05)。治疗1个月后PSR4降低,与治疗前比较,差异有统计学意义(P<0.05)。治疗1、2个月后,患者的舌象润燥指数升高,腻腐指数升高,与治疗前比较,差异均有统计学意义(P<0.05);治疗1个月后,舌象厚薄指数降低,裂纹指数升高,与治疗前比较,差异有统计学意义(P<0.05)。结论:舌脉象客观检测参数可作为中西医结合治疗肺癌临床疗效评价的参考指标之一。Objective： To observe the changes of tongue and pulse parameters in lung cancer patients after combined treatment with integrated traditional Chinese and Western medicine, and to probe into the application of the tongue and pulse parameters in evaluation of integrated traditional Chinese and Western medicine therapy on lung cancer patients. Methods： Electropulsograms and tongue pictures of 50 lung cancer patients were examined by TP- I digital electropulsography. The tongue and pulse parameters of the patients, including the indexes of moistness and dryness, thinness and thickness, fissure, swollenness and emaciation, greasiness and likeness of curd, and power spectral ratios （PSRs） 1, 2, 3, 4 and cepstrum spectral ratios （CSRs） 1, 2, 3, 4, were observed after 1- and 2-month treatment with Yifei Kangliu Oral Liquid （a compound traditional Chinese herbal medicine） plus chemotherapy, respectively. The above parameters of the lung cancer patients were compared before and after the treatment. Results： PSR1 increased, while PSR2 decreased significantly after 1- and 2-month treatment as compared with before treatment （P〈0.05）. PSR1 decreased, while PSR2 increased after 2-month treatment as compared with after l-month treatment （P〈0.05）. PSR4 after 1-month treatment was lower than before treatment （P〈0.05）. The tongue parameters including the indexes of moistness and dryness, and greasiness and likeness of curd increased significantly after 1- and 2-month treatment as compared with before treatment （P〈0.05）. The index of thinness and thickness decreased, while the index of fissure increased significantly after 1-month treatment as compared with before treatment （P〈0.05）. Conclusion. Tongue and pulse parameters can be regarded as one of reference indexes in evaluation of integrated traditional Chinese and Western medicine therapy on lung cancer patients.

关 键 词：舌色 舌苔 脉象图 肺癌 治疗效果 结果评价 

分 类 号：R734.2[医药卫生—肿瘤] R241[医药卫生—临床医学]