偏振光皮肤镜图像分析技术在临床上开发应用的研究——在皮肤肿瘤诊断中的灵敏度与特异度探讨  

Clinical Application Study of the Polarized-Light Dermoscopy Image Analysis Technique——A study of its sensitivity and specificity in the diagnosis of skin tumor

作　　者：孟如松[1] 赵广[1] 蔡瑞康[1] 姜志国[2] 孟晓[3] 

机构地区：[1]全军皮肤病研究所空军总医院皮肤科,北京100036 [2]北京航空航天大学,北京100083 [3]首都医科大学,北京100069

出　　处：《CT理论与应用研究（中英文）》2009年第1期88-93,共6页Computerized Tomography Theory and Applications

基　　金：国家自然科学基金项目(60672152)

摘　　要：目的:探讨偏振光皮肤镜(DP)图像分析技术在皮肤肿瘤诊断中的价值。方法:在临床肉眼诊断的基础上,采用DP法对皮肤肿瘤进行辅助诊断,后经组织病理确诊,将诊断结果进行对照与回顾性分析。结果:总结了948例皮肤肿瘤和与其相鉴别的色素性皮损的DP法诊断指征并显示出平均灵敏度88.77%,特异度94.92%,诊断符合率达92.72%,比临床肉眼诊断符合率提高了23.94%。结论:DP法是一种无创性观察体表和表皮下部肉眼无法识别的形态学特征与数字图像技术。它对多种皮肤肿瘤尤其对色素性皮肤肿瘤的判断和良恶性皮损的鉴别诊断具有较好的辅助诊断价值。对减少盲目活检、有效指导手术切除范围和选择合理的治疗方法及术后复诊具有重要意义。Objective： To study the value of polarized-light dermoscopy （DP） image analysis technique in the diagnosis of skin tumors. Method： On the basis of visual diagnosis, DP diagnosis of skin tumor is carried out, and after histopathological diagnosis, comparison and retrospective analysis are made on the diagnostic results. Results： Diagnostic indicators of 948 cases of skin tumor and pigmented skin lesion with DP technique have been summarized, which show that the average sensitivity is 88.77%, specificity 94.92% and accuracy 92.72%, i.e. 23.94% higher than the accuracy of visual diagnosis. Conclusion： DP is a non-invasive imaging technique for observing and characterizing epidermal and subepidermal tissue. It is a useful auxiliary method for diagnosing various skin tumors, especially pigmented skin tumor, and identifying benign and malignant skin tumors. Therefore, DP technique is of great importance for avoiding blind biopsy, providing effective information for resection range and selecting the most reasonable therapy.

关 键 词：偏振光皮肤镜 皮肤肿瘤 色素性皮损 灵敏度 特异度 

分 类 号：R739.5[医药卫生—肿瘤]