去甲长春花碱与顺铂联合方案治疗晚期非小细胞肺癌的临床观察  

Clinical Observation of Treatment to Advanced Late Non-small Cell Carcinoma of Lung with NP Program

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作  者:胡英春 王怀瑾[2] 

机构地区:[1]辽宁省大连市瓦房店市第三医院肿瘤科,116300 [2]大连大学附属医院肿瘤中心

出  处:《医学理论与实践》2009年第3期263-264,共2页The Journal of Medical Theory and Practice

摘  要:目的:观察去甲长春花碱与顺铂(NP)方案治疗非小细胞肺癌的近期疗效。方法:NVB25mg/m^2,静脉注射,第1,8天;DDP20mg/m^2,静脉滴注(不水化),第1~4天。21d为1个周期,32例病人全部进行3个周期化疗。结果:CR2例(6.25%),PR9例(28.1%),SD13例(40.6%),PD8例(25%),有效率为33.3%。结论:NP方案对于晚期非小细胞肺癌病人是一个安全有效的联合化疗方案。Objective:To observe the recent therapeutic effect of non-small cell carcinoma of lung(NCCN)with NP program. Methods: NVB 25mg/m^2 was administered intravenously on the 1st and eighth day and DDP 20mg/m^2 (nonhydrate) ,on the 1st to fourth day. A period lasted twenty-one days. All of thirty two cases were treated for three periods. Results.. CR occured in 2 cases(6. 25%) ,PR in 9 cases(28. 1%) ,SD in 13 cases(40. 6%) ,PD in 8 cases (25. 0%), effective rate was 33. 3%. Conclusion: As a combined chemotherapy the NP program is a safe and and effective therapy for the advanced NCCN.

关 键 词:异长春花碱/治疗应用 顺铂/治疗应用 非小细胞肺癌/药物疗法 

分 类 号:R734.2[医药卫生—肿瘤]

 

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