应用hydrocoil与单纯裸弹簧圈栓塞颅内动脉瘤的疗效对比分析  

Embolization of intracranial aneurysm with HydroCoils verus inert platinum coils: Effect on packing density, coil length and quantity, cost and durability of therapy

作　　者：杨东虹[1] 唐文渊[2] 许民辉[1] 陈立朝[1] 

机构地区：[1]第三军医大学大坪医院神经外科,重庆400042 [2]重庆医科大学附属第一医院神经外科,重庆400016

出　　处：《中国现代医学杂志》2009年第5期705-708,共4页China Journal of Modern Medicine

摘　　要：目的评价hydrocoil和裸弹簧圈在填塞率、弹簧圈长度和数量、治疗费用及治疗的远期效果。方法选取该该科2005年12月～2007年6月使用hydrocoil栓塞的40例颅内动脉瘤,同时选取2000～2005年间40例在体积和形状相似使用单纯裸弹簧圈栓塞的颅内动脉瘤作为对照组。对比指标包括填塞率(VPO)、弹簧圈长度和数量、弹簧圈的费用、治疗的稳定性。结果hydrocoil治疗组较裸圈组获得明显的高填塞率(VPO)(84.8%～29.8%;P<0.001),降低了每个动脉瘤的弹簧圈总长度(33.2～44.3cm),但增加了治疗费用(58350～40170元)。造影随访时间平均为10.6个月,较裸圈组显示较低的复发率(12%～24%)。结论使用hydro-coil栓塞颅内动脉瘤可显著提高致密填塞率、减少弹簧圈使用长度,降低复发率和再治疗率。[Objective] To examine the effect of packing density achieved with HydroCoils versus inert platinum coils on durability of aneurysm therapy. The effect of HydroCoil use on total coil number and coil length used, total coil cost, was also evaluated. [Methods] Forty aneurysms embolized primarily using HydroCoils from 2005 to 2007 were compared with 40 volume-shape-matched aneurysms treated with standard platinum coils from 2000 to 2005. Outcome measures included volumetric percentage occlusion （VPO）, length and number of coils used, coil cost and durability Of therapy. [Results] Forty aneurysms treated with HydroCoils were matched with 40 aneurysms treated with inert platinum. HydroCoil embolization yielded significandy greater VPO （84.8% versus 29.8%; P 〈0.001）, de- creased average total coil length used per aneurysm （33.2 versus 44.3 era）. Follow-up angiography at mean 10.6 months revealed lower aneurysm recurrence rates （12% versus 24%）. Initial costs associated with HydroCoil embolization were higher （RMB 58350 versus RMB 40170. P =0.004） but countered by lower retreatment rates （6% versus 18%）. [Conclusions] HydroCoil embolization achieves greater aneurysm packing density with decreased coil length. Initial durability data favor HydroCoils, with lower recurrence and retreatment rates.

关 键 词：脑动脉瘤 HYDROCOIL 栓塞 

分 类 号：R732.21[医药卫生—肿瘤]