SPECT/CT同机融合在恶性肿瘤侵犯下颌骨中的诊断价值  

The value of SPECT/CT in diagnosis of malignant tumors invasion of mandible

作　　者：段青云[1] 贾暮云[2] 张雄[1] 袁荣涛[2] 卜令学[2] 尚伟[2] 赵杰[3] 左书耀[4] 金晓明[2] 李宁毅[2] 

机构地区：[1]浙江省杭州市第一人民医院口腔科,310006 [2]青岛大学医学院附属医院口腔颌面外科 [3]青岛大学医学院附属医院病理科 [4]青岛大学医学院附属医院核医学科

出　　处：《实用口腔医学杂志》2009年第2期251-255,共5页Journal of Practical Stomatology

摘　　要：目的:研究SPECT/CT同机融合骨扫描在恶性肿瘤侵犯下颌骨中的诊断价值。方法:选择43例口腔恶性肿瘤侵犯下颌骨而行下颌骨节段性或半侧下颌骨切除的患者,分为A(外周侵犯型)、B(中心侵犯型)2组,对比研究SPECT/CT骨扫描和组织病理学检查的下颌骨病变范围。结果:A组:SPECT/CT显示的下颌骨受侵犯的范围较病理检查高估(1.02±0.20)cm,二者的差异有高度统计学意义(P<0.01)。B组:SPECT/CT比病理检查高估(1.3±0.39)cm,二者的差异亦有高度统计学意义(P<0.01)。A、B组相比较,SPECT/CT和病理检查之间的差异并无统计学意义(t=1.656,0.446,P>0.05)。结论:SPECT/CT显示的病变范围符合手术需要切除的合理范围,对下颌骨病变的定位及定量等方面具有明显的优势,是临床检查的理想工具。Objective：To estimate the value of SPECT/CT in diagnosis of oral malignant tumors invasion in mandible. Methods： Forty-three patients with carcinoma invasion in mandible, which all received segmental mandibulectomy, were divided into two groups, group A （invasion to surrounding） and group B （invasion to center）. The carcinoma invasion in mandible was detected by SPECT/CT scan and pathological examination. Results： Group A：The extent of carcinoma invasion in mandible of SPECT/CT was 1.02 ± 0.20 cm bigger than that of pathological examination. Group B：The extent of carcinoma invasion in mandible of SPECT/CT was 1.3 ± 0.39 cm bigger than that of pathological examination. Between group A and B, the differences between SPECT/CT and pathology determining the extent of carcinoma invasion of mandible was not significant（ t = 1. 656,0. 446;P 〉 0.05 ） . Conclusion： The extent of carcinoma invasion in mandible by SPECT/CT scan was adequate for operational safety margin to do mandibulectomy. SPECT/CT is an ideal instrument to determine the extent of carcinoma invasion of mandible.

关 键 词：SPECT/CT 病理学 下颌骨 恶性肿瘤 

分 类 号：R739.8[医药卫生—肿瘤]