支架孔率对脑动脉瘤血流动力学影响的三维数值模拟研究  

Influence of stent porosity on cerebral intra-aneurysmal hemodynamics:a three-dimensional numerical simulative study

作　　者：张星[1] 黄清海[1] 施洋[2] 余钊胜[2] 邵雪明[2] 刘建民[1] 

机构地区：[1]第二军医大学长海医院神经外科,上海200433 [2]浙江大学流体力学研究所

出　　处：《介入放射学杂志》2009年第3期213-216,共4页Journal of Interventional Radiology

基　　金：上海市优秀学科带头人项目(07DX14026);上海市自然科学基金项目(08ZR1406200)

摘　　要：目的探讨不同支架网孔密度对支架植入后脑动脉瘤内血流动力学的影响。方法建立宽颈的弯曲管侧壁型动脉瘤血流动力学三维数值模型,比较不同网孔密度支架植入前后,动脉瘤内血流动力学变化。结果动脉瘤远侧壁的速度峰值与壁面剪应力随着支架孔率下降而降低,瘤颈远侧壁及瘤顶部的压力场与支架孔率无明确的相关性。结论数值模拟研究证实支架孔率是影响动脉瘤内血流动力学的关键因素,合适的支架孔率设计对动脉瘤血管重建治疗至关重要。Objective To investigate the influence of stent properties on the alteration of cerebral intra-aneurysmal hemodynamics. Methods A wide-necked sidewall aneurysm model in a curved-vessel was created by using computational fluid dynamics simulations. The hemodynamic changes after deployment of the stent with different porosity were studied. Results The peak velocity and the wall shear stress correlated well with the porosity of the stents. The pressure in aneurysmal sac showed no changes with different stent porosities. Conclusion This numerical simulation study indicates that the stent porosity is an important factor which has significant effect on the hemodynamies inside the aneurysm. Appropriate stent porosity is very important for the treatment of wide-neck intracranial aneurysms.

关 键 词：脑动脉瘤 血流动力学 计算流体力学 支架 孔率 

分 类 号：R743[医药卫生—神经病学与精神病学]