颈交感神经节注射治疗顽固性点状角膜炎的应用报告  

Application of Injection Treating Obstinate Punctate Keratitis inNeck Sympathetic Nerve Ganglion

作　　者：朱思泉[1] 吴笑梅[1] 许冰 

机构地区：[1]中山医科大学第三临床学院眼科,510630

出　　处：《伤残医学杂志》1998年第1期23-25,共3页Medical Journal of Trauma and Disability

摘　　要：本文目的是探讨颈文感神经节注射治疗某些顽固性点状角膜炎的临床效果及其机制．方法是对临床上经常规药物治疗仍反复发作的点状角膜炎患者，先用PCR法排除病毒感染，再用经颇多普勒（TCD）和交感神经功能定量检查提示有交感神经功能紊乱后，利用自行设计的颈节交感神经节注射法治疗，并进行自身对照分析．结果36例顽固性点状角膜炎有12例TCD提示同侧眼动脉痉挛，24例示大脑前动脉痉挛，均伴有不同程度的眶上神经压痛及眼干涩等症状，交感神经功能定量分析提示有不同程度的交感神经功能紊乱．颈交感神经节注射治疗后第1天角膜荧光着色阴性10只眼，3次-5次注射后完合治愈32只（88.9％），随访6月－18月，复发12只眼，（33．3％），再注射一疗程随访无复发．结论，颈交感神经节注射是治疗某些顽固性点状角膜炎的有效方法，值得在临床上推广．推测交感神经功能障碍所致的角膜缘血管网供血功能紊乱，角膜上皮细胞营养及代谢障碍可能是顽固性点状角膜炎发病的主要原因．To investigate th technique of neck sympathetic nerve ganglion injechon treatingobstinate punctate keratitis and evaluate its effects. The methods was repeatedly punctate keratihs afterroutined treatment, who were removed virus diseases by PCR, determined sympathetic nerve functiondamage by TCD and sympathetic nerve measured analysis, were treated by neck sympathehc nerveganglion injection. Results, 12 cases of all cases were the tensity of ophthalmic artery, 24 cases were thetensity of cerebral anterior. Supraorbital neural pain. dry eyes and sympathehc nerve function damagewere discovered in all cases. ic eyes cornea were well demonstrated with nuorescein posttreatlnent oneday, 32 eyes (88.9%) were healed with 3 - 5 injections, follow up 6 ~ 18 months, 12 eyes (33.3 %) reply,no one reply 1 injection too. Conclution. the neck sympathetic nerve ganglion injection was very good toobstinate punctate keratitis and was worthy to be spread. We infered the major cause of obstinatepunctate keratitis may be vasonerve damage of comeal edge vascularization, comeal epithelial cellnutrition and metabolism obstruction

关 键 词：颈交感神经节 注射 点状角膜炎 角膜炎 治疗 

分 类 号：R772.210.5[医药卫生—眼科]