黄芪颗粒治疗复发性阿弗他溃疡的远期疗效观察  

Long-term Effect Observation of Astragalus Granule on Recurrent Aphthous Ulcer

作　　者：谢扬兵 周贤刚[1] 许明德[1] 

机构地区：[1]四川省隆昌县人民医院,四川隆昌642150

出　　处：《儿科药学杂志》2009年第2期15-17,共3页Journal of Pediatric Pharmacy

摘　　要：目的:评价黄芪颗粒治疗复发性阿弗他溃疡的远期疗效和安全性。方法:将80例复发性阿弗他溃疡患者随机分为治疗组和对照组,每组各40例。治疗组在常规药物消炎止痛治疗的基础上再给予口服黄芪颗粒3个月;对照组仅给予常规药物消炎止痛治疗。治疗组在口服黄芪颗粒3个月后与对照组一同进行为期6个月的疗效跟踪评定。结果:治疗组6个月内的溃疡复发次数、溃疡总数、溃疡平均愈合天数分别为(6.71±2.58)次、(10.09±2.92)个、(4.94±1.63)d,均优于对照组[(13.53±5.77)次、(27.97±8.14)个、(12.35±4.28d)],差异有统计学意义(P<0.05)。未发现治疗组有任何毒副作用。结论:黄芪颗粒治疗复发性阿弗他溃疡具有远期疗效肯定、使用方便、安全性高等优点,值得在临床上推广应用。Objective： To assess the long-term efficacy and safety of Astragalus granule in treatment of recurrent aphthous ulcer. Methods： Eighty patients of recurrent aphthous ulcer were randomly divided into treatment group and control group, 40 patients in each group. The treatment group was treated with conventional anti-inflammatory and analgesic drugs combined with oral Astragalus granule for 3 months, and the control group with single conventional anti-inflammatory and analgesic drugs only. Three months later, their therapeutic effects were observed. Results：In the 6-months observation period, the times of ulcer recurrence, the total number of ulcers and the mean healing days （6.71 ±2.58, 10.09±2.92, 4.94 ± 1.63 ） in the treatment group were better than those （ 13.53± 5.77, 27.97 ±8. 14, 12.35 ±4. 28 ） in the control group with significant differences between the two groups （ P 〈 0.05 ）. No adverse effect was found in the observation. Conclusions： Long-term efficacy and safety of astragalus granule in treatment of recurrent aphthous ulcer are obvious and worth promoting.

关 键 词：复发性阿弗他溃疡 黄芪颗粒 远期疗效 

分 类 号：R781.5[医药卫生—口腔医学] R287.82[医药卫生—临床医学]