天然型无机骨修复良性溶骨性骨缺损的临床观察  

CLINICAL OBSERVATION ON BENIGN OSTEOLYTIC BONE DEFECTS TREATED WITH NATURAL NONORGANIC BONE

作　　者：李鼎锋[1] 戴景蕊[1] 马贵骧 

机构地区：[1]中国医学科学院中国协和医科大学肿瘤医院骨瘤科

出　　处：《中国修复重建外科杂志》1998年第4期220-222,共3页Chinese Journal of Reparative and Reconstructive Surgery

摘　　要：为寻找良性骨缺损理想的充填材料，特别是修复儿童良性溶骨性较大的骨缺损，采用天然型无机骨（ＮＮＢ）充填良性溶骨性骨缺损５例，其中骨囊肿３例，纤维异样增殖症１例，非骨化性纤维瘤１例。病变位于股骨中上段１例，股骨下段３例，肱骨上段１例。５例均行病灶开窗刮除，彻底清除内膜及瘤样病变。充填方块状ＮＮＢ，术后伤口均Ⅰ期愈合。术后３个月～６个月活动正常。术后Ｘ线片复查见方块状ＮＮＢ间及其内的间隙影消失，新生骨与周围骨壳融合，显示病灶愈合。经７个月～２年随访，病变区无复发。认为，ＮＮＢ是修复良性溶骨性骨缺损理想的充填材料。It is extremely necessary to find an ideal filling material for the treatment of benign bone defect, particularly those benign osteolytic defect in children with a comparatively large cavity. From July, 1995 to December, 1996, 10 cases of benign osteolytic bone defects were treated, in which 5 cases of benign osteolytic defects, 3 cases of bone cysts, 1 case of fibrous dysplasia of bone and 1 case of nonossifying fibroma. After thorough curettage of the cavity, the natural nonorganic bone in cubeshaped was used to fill the prepared cavity. The results showed that the activities of the patients resumed normal in 3 to 6 months after operation. The roentgenographic examination after operation showed that the lucent spaces between NNB cubes disappeared with obvious new bone formation and the bony cavity was obliterated with newlyformed bone. There was no recurrence of the lesion during a followup of 7 to 24 months. It was concluded that to treat the osteolytic defect of bone with NNB was a method of choice. The new bone formation appeared early in large amount and increased rapidly.

关 键 词：骨肿瘤 骨缺损 天然型无机骨 修复 NNB 

分 类 号：R738.105[医药卫生—肿瘤] R318.08[医药卫生—临床医学]