腹腔镜与同期开腹结直肠癌根治术的对比分析  

Comparative Analysis of Laparoscopic and Open Cholectomy and Rectomy for Colorectai Carcinoma

作　　者：赵楚雄[1] 洪楚原[1] 梁国健[1] 邓一文[1] 

机构地区：[1]广州医学院第二附属医院胃肠外科,广州510260

出　　处：《中国医药导刊》2009年第2期227-229,共3页Chinese Journal of Medicinal Guide

摘　　要：目的:比较腹腔镜结直肠癌切除术与同期开腹手术的临床疗效。方法:将2005年6月至2008年6月行结直肠癌切除的患者根据意愿分为接受腹腔镜手术和传统开腹手术2组,对比2组的手术安全性、术后恢复情况、肿瘤根治性和随访结果。结果:腹腔镜组和开腹组分别有65、60例患者入选.两组均无术中、术后严重并发症和手术死亡病例,腹腔镜组2例中转开腹手术;腹腔镜组术中失血量为(109.38±26.45)ml.显著少于开腹组(162±52.32)ml(P<0.05):下床活动时间腹腔镜组为(49.52±10.528)h,显著短于开腹组的(62.75±1.66)h(P<0.05).腹腔镜组手术清扫淋巴结总数(8.88±3.3)粒与开腹组(8.95±3.4)粒差异无统计学意义(P>0.05);两组病例均随访6～36个月,两组短期(≤3年)累计生存率差异无统计学意义(P>0.05)。结论:腹腔镜结直肠癌切除术安全、有效,具有可行性。Objective： To compare the results of taparoscopic and open cholectomy and rectomy for cnlorectal carcinoma. Methods：We compared operation safety, recovery, complications,lymph nodes clearance and short term outcome for the two groups of patients under going either laparoscopie or open operation for colorectal carcinoma. Results： Between Jun 2005 and Jun 2008.65patients underwent a laparoscopic cholectomy or rectomy;60 patients were treated by open approach,2 patients in the laparoscopic group were converted to open surgery. The mean blood loss in laparoscopic group （ 109. 38 ± 26.45 ） rrd was less than that in open group （ 162 ± 52. 32 ） ml （ P 〈 0.05 ）, Time to resume early activity in laparoscopic group were （49.52± 10. 528 ） h, which were significantly shorter than those in open group（62.75 ±1. 66 ） h （ P 〈 0.05 ）. No significant difference between the two groups was observed for the lymph nodes clearance （ P 〉 0.05 ）, The mean follow up time of the two groups were 6 -36 months respectively, Local recurrence rate, metastases rate and cumulative survival probability at 3 years were similar for the two groups. Conclusions：Laparoscopic cholectomy and rectomy for colorectal carcinoma can be performed safely,effectively with the adventages of minimal invasiveness.

关 键 词：结直肠癌 腹腔镜 切除术 

分 类 号：R735.3[医药卫生—肿瘤]