甲氧苄胺嘧啶药物的非破坏分析  

Noninvasive Analysis of Trimethoprim Powder Pharmaceutical

作　　者：任玉林[1,2] 李伟[1,2] 郭晔 任玉秋[1,2] 张璐 孙莹[3] 惠春[3] 

机构地区：[1]吉林大学化学系 [2]白城卫生学校 [3]长春医学高等专科学校药学系

出　　处：《分析试验室》1998年第2期27-29,共3页Chinese Journal of Analysis Laboratory

摘　　要：将偏最小二乘（ＰＬＳ）法同近红外漫反射光谱法结合，非破坏分析了粉末药品甲氧苄胺嘧啶。讨论了波长对ＰＬＳ定量预报能力的影响。校正样品和预测样品的预测结果相对标准误差分别为０．３３％和１．３９％。Trimethoprim powder pharmaceutical was analysed noninvasively by nearinfrared diffuse reflectance spectra conbined with partial least squares method .The influence of the wavelength on the capacity of quantitative prediction of partial least squares method is discussed.The relative standard errors of prediction for the calibration samples and prediction samples are 0.33% and 1.39% respectively .The results are satisfactory.

关 键 词：甲氧苄胺嘧啶 非破坏分析 PLS法 近红外 光谱法 

分 类 号：R914.1[医药卫生—药物化学]