L-苏氨酸发酵液有机膜过滤工艺研究  

Research of L-threonine Broth Filtration Process by Organic Membrane

作　　者：黄金[1] 陈宁[1] 温廷益[2] 

机构地区：[1]天津科技大学生物工程学院,天津300457 [2]中国科学院微生物研究所,北京100101

出　　处：《食品与发酵工业》2009年第2期87-90,共4页Food and Fermentation Industries

基　　金：国家高技术研究发展计划“863项目”(2006AA02Z216)

摘　　要：采用有机微滤-超滤膜分离系统,两阶段截留发酵液中残留的菌体、蛋白质和悬浮固体颗粒,建立了微滤-超滤有机膜两步法过滤工艺,解决了一步法超滤过程中的膜通量低的难题。膜通量由8.25 L/(m2.h)提高至32 L/(m2.h),色素去除率、蛋白去除率及产品回收率可分别达到58.5%、97.6%和87.0%。另外,采用0.01 mol/L NaOH、自来水和0.1 mol/L HCl间歇替换清洗可有效恢复膜通量。The micro-filtration and ultra-filtration organic membrane system was applied to extract L- threonine from broth and its two-step process for removing protein, biomass and suspended solid granule was established. The process resolved the lower membrane flux difficulties of one step ultra-filtration process. The removal ratio of protein and pigment was 97.6 % and 58.5 % respectively. The ultra-filtration flux was increased from 8.25 L/（m^2· h） to 32 L/（m^2·h） and the recovery ratio of L-threonine was 87.0%. In addition, membrane flux can be resumed efficiently with intermittent replacement of 0.01mol/L NaOH, tap water and 0. 1mol/L HCl.

关 键 词：有机膜 L-苏氨酸 分离 超滤 

分 类 号：TQ922[轻工技术与工程—发酵工程]