36例胃间质瘤临床诊治分析  

Diagnosis and treatment of gastrointestinal stromal tumors:A clinical analysis of 36 Cases

作　　者：滕华安 董家刚[1] 

机构地区：[1]四川省宜宾市第三人民医院普外科,644000

出　　处：《大家健康（学术版）》2011年第23期4-6,共3页

摘　　要：目的分析研究胃肠间质瘤的临床诊断和外科治疗方法。方法回顾性分析2001年2月至2011年2月期间在我院经手术证实的36例胃肠道间质瘤患者的临床资料。结果 36例患者中临床症状表现为上腹部不适或疼痛15例,上消化道出血、黑便12例,腹部包块4例,体检发现5例。其中行胃楔形切除术16例,近端胃大部切除术7例,远端胃大部切除术10例,全胃切除3例。免疫组化结果,CD117阳性率为86.11%,CD34阳性率为80.56%。全组均行手术治疗,无手术死亡病例。结论胃间质瘤的诊断主要依靠术后病理切片及免疫组化,CD117是胃肠道间质瘤的特异性诊断指标,手术是治疗胃肠间质瘤的主要方法。Objective To explore the diagnosis and treatment of gastrointestinal stromal tumors.Methods A retrospective analysis of clinical data was conducted in 36 patients with GISTs who were admitted in our hospital from February 2001 to February 2011.Results The clinical manifestation was found in patients with GIST included abdominal pain or discomfort in 15 cases,gastrointestinal bleeding or melena in 12 cases,abdominal mass in 4 cases,and 5 cases is found in physical examination.All of GISTs in this group were surgically removed,with no operative deaths.Local wedgy resection was performed in 16 cases,proximal partial gastrectomy in 7 cases,distal partial gastrectomy in 10 cases,total gastrectomy in 3 cases,Immunohistochemical determination revealed that the positive rate of CD117 and CD34 was 86.11% and80.56%.Conclusion The preoperative diagnosis of GISTs is difficult.The pathological examination and immunohistochemical staining are key issues in confirming the diagnosis the and surgery is the main therapy.

关 键 词：胃肠道间质瘤 诊断 治疗 

分 类 号：R735[医药卫生—肿瘤]