53例胃肠道类癌临床病理分析  

Clinicopathologic Analysis of 53 Cases of Gastrointestinal Carcinoid Tumor

作　　者：袁海洪[1] 张连郁[2] 

机构地区：[1]天津市武清区人民医院病理研究室,天津市301700 [2]天津医科大学附属肿瘤医院病理研究室

出　　处：《中国肿瘤临床》2009年第7期372-374,共3页Chinese Journal of Clinical Oncology

摘　　要：天津市武清区人民医院病理研究室天津市 301700Objective： To explore the clinical and pathological characteristics of gastrointestinal carcinoid tumors （GICT） and to investigate methods for diagnosing GICT. Methods： The clinical materials of 53 cases of GICT seen in Wuqing People＇s Hospital and Cancer Institute and Hospital of Tianjin Medical University between January 1995 and December 2006 were retrospectively analyzed. Results： Of the 53 cases, 18 cases had tumor lesions in the appendix, 12 cases had lesions in the rectum, 8 cases had lesions in the colon, 7 cases had lesions in the stomach, 5 cases had lesions in the small intestine, and 3 cases had lesions in the duodenum. All of the patients were treated with surgical excision and the diagnosis was confirmed by endoscopic biopsy or surgery. Of the 53 cases, 28 cases were diagnosed by endoscopic biopsy before surgery. Eight cases presented with carcinoid syndrome, and 18 cases died of metastases. The main clinical manifestations of patients were stomachache in 40 cases （75.5%）, sensation of fullness after eating in 4 cases （7.5%）, changes in defecation habits in 15 cases （28.3%）, emaciation in 12 cases （22.6%）, mucopurulent bloody stool in 7 cases （13.2%）, incomplete intestinal obstruction in 8 cases （15.1%）, abdominal mass in 10 cases （18.9%） and carcinoid syndrome in 8 cases （15.1%）. There were three types of GICT： typical, atypical and parvicellular. Conclusion： The diagnosis of GICT mainly depends on pathological detection and immunohistochemistry. Tumor size, differentiation, infiltration, local lymph node invasion, and metastasis are correlated to prognosis. Surgery is the best choice for the treatment of GICT.

关 键 词：胃肠道 肿瘤 类癌 病理学 

分 类 号：R735[医药卫生—肿瘤] R197.32[医药卫生—临床医学]