高强度聚焦超声治疗结直肠癌肝转移14例临床观察  

High intensity focused ultrasound is treatment of 14 hepatic metastases from colorectal cancer

作　　者：孙艳[1] 钟喻[1] 伍强[1] 李若桦[1] 

机构地区：[1]广东医学院附属深圳福田人民医院肿瘤科,518033

出　　处：《肿瘤研究与临床》2007年第6期407-408,共2页Cancer Research and Clinic

摘　　要：目的探讨高强度聚焦超声(HIFU)治疗结直肠癌肝转移的安全性及有效性。方法14例结直肠癌术后肝转移患者20个病灶行HIFU治疗,观察患者的生命体征、主要脏器功能、MRI检查结果、不良反应情况。结果所观察14例患者中生命体征均平稳,肝肾功能正常,Karnofsky评分升高5例,14例患者20个病灶磁共振成像(MRI)检查治疗区信号明显减低,血供消失,边缘见一薄层水肿强化带6例患者皮肤出现条索状灼痕。结论HIFU是一种安全、有效的治疗结直肠癌肝转移的方法。Objective To evaluate the clinical safety and efficacy of HIFU treatment of hepatic metastases from colorectal cancer.Methods 20 tumor lesions in 14 patients with hepatic metastases from colonectal cancer were treated with HIFU therapy.The vital signs,main organs'functions,examination of MRI and complications were observed.Results Vital signs of all the 14 patients were stable.The function of liver and kidney were normal and life quality were improved with elevation of Karnofsky in 5 patients.On MRI examination,the MRI signals of treating area of 20 tumor lesion in 14 patients decreased remarkably with disappearance of blood supply and a thin layer of edematous intensified zone was detected on the margin of lesion.6 patients were found to have cord-like burning scar on skin.Conclusion HIFU treatment is safe and effective in treatment of hepatic metastases from colorectal cancer.

关 键 词：超声 高强聚焦 结肠 肝肿瘤 治疗 

分 类 号：R735.3[医药卫生—肿瘤]