Microbial production of natural poly amino acid  

作　　者：SHI Feng XU ZhiNan CEN PeiLin 

机构地区：[1]Institute of Bioengineering,Department of Chemical Engineering and Bioengineering,Zhejiang University,Hangzhou 310027,China [2]Shandong Province Institute of Drug Control,Jinan 250012,China

出　　处：《Science China Chemistry》2007年第3期291-303,共13页中国科学（化学英文版）

基　　金：Supported by the Ministry of Science and Technology (Grant No. 2006AA02Z239)

摘　　要：Three kinds of poly amino acids, poly-γ-glutamic acid, poly(ε-L-lysine) and multi-L-arginyl-poly (L-aspartic acid) can be synthesized by enzymatic process independently from ribosomal protein biosynthesis pathways in microorganism. These biosynthesized polymers have attracted more and more attentions because of their unique properties and various applications. In this review, the current knowledge on the biosynthesis, biodegradations and applications of these three poly amino acids are summarized.Three kinds of poly amino acids, poly-γ-glutamic acid, poly(?-L-lysine) and multi-L-arginyl-poly (L-aspartic acid) can be synthesized by enzymatic process independently from ribosomal protein biosynthesis pathways in microorganism. These biosynthesized polymers have attracted more and more attentions because of their unique properties and various applications. In this review, the current knowledge on the biosynthesis, biodegradations and applications of these three poly amino acids are summarized.

关 键 词：POLY AMINO ACID BIOSYNTHESIS METABOLISM application 

分 类 号：TQ922.9[轻工技术与工程—发酵工程]