Management of hemangiopericytomas in the central nervous system  

中枢神经系统血管外皮细胞瘤的诊断与治疗(英文)

作　　者：杜固宏[1] 周良辅[1] 李士其[1] 毛颖[1] 陈宏[2] 

机构地区：[1]复旦大学医学院附属华山医院神经外科,上海200040 [2]复旦大学医学院附属华山医院神经病理科,上海200040

出　　处：《Chinese Medical Journal》2001年第8期12-15,102,共5页中华医学杂志（英文版）

摘　　要：Objective　To elucidate the clinical features and treatment of Hemangiopericytomas (HPCs) in the central nervous system. Methods　Twenty-six HPC operations performed at Huashan Hospital from January 1993 to June 1999 were analyzed retrospectively, and a review of relevant literatures was done. Results　Among the 26 cases, total tumor removal was achieved in 24 cases, and subtotal removal in 2 cases. Postoperatively, neurological symptoms were improved or unchanged in 21 cases, worsened in 4 cases, and pneumonia caused death in 1 case. Eighteen patients received postoperative radiotherapy. Eighteen patients were followed up from 1 month to 58 months (average, 22 months). During the follow-up period, 2 patients presented one or more distant metastasis, and one patient died of recurrence. Conclusion　Surgical management is the best choice for treatment of patients with HPCs. Postoperative radiotherapy can postpone the risk of tumor recurrence.目的　血管外皮细胞瘤是少见的中枢神经系统肿瘤 ,由于其易复发和转移而预后不良。本文介绍 2 6例血管外皮细胞瘤的处理经验并结合文献复习其诊治要点。方法　回顾性分析 1993年 1月至 1999年 6月华山医院收治的 2 6例血管外皮细胞瘤 ,其中 5例为复发肿瘤 ,1例为术后残留。结果　 2 6例中 2 4例病灶全切除 ,2例次全切除。术后 2 1例症状好转或不变 ,4例加重 ,1例手术后死于并发症。18例术后放疗。 18例获随访 ,随访期 1- 5 8个月 ,其中 15例恢复良好 ,2例发现转移肿瘤 ,1例复发再次手术后死亡。结论　手术全切是主要治疗方法 ,术后放疗可延缓肿瘤复发。

关 键 词：hemangiopericytoma  ·   surgery  ·  radiotherapy 

分 类 号：R739.4[医药卫生—肿瘤]