Studies on the creatine kinase MM isoforms of normal and Duchenne muscular dystrophic patients  

作　　者：赵昕 毕春雷 杨振华 

出　　处：《Chinese Medical Journal》1998年第1期75-77,共3页中华医学杂志（英文版）

摘　　要：OBJECTIVE: To study the changes of creatine kinase MM (CK-MM) isoforms in Duchenne muscular dystrophy (DMD) patients. METHODS: Serum samples from 49 DMD patients and 40 control subjects were collected for CK-MM isoforms measurement. CK-MM isoforms were separated within 30 minutes by electrophoresis on agarose gel with a discontinuous buffer system at constant current of 30 mA and low voltage of 200-300 V, then measured by fluorescence scanning. RESULTS: Significant differences of MM2/MM1 ratio were found between DMD patients and control subjects (POBJECTIVE: To study the changes of creatine kinase MM (CK-MM) isoforms in Duchenne muscular dystrophy (DMD) patients. METHODS: Serum samples from 49 DMD patients and 40 control subjects were collected for CK-MM isoforms measurement. CK-MM isoforms were separated within 30 minutes by electrophoresis on agarose gel with a discontinuous buffer system at constant current of 30 mA and low voltage of 200-300 V, then measured by fluorescence scanning. RESULTS: Significant differences of MM2/MM1 ratio were found between DMD patients and control subjects (P

关 键 词：Adolescent Adult Biological Markers CHILD Child  Preschool Creatine Kinase Electrophoresis  Agar Gel Female Humans ISOENZYMES Male Muscular Dystrophies 

分 类 号：R746.2[医药卫生—神经病学与精神病学]