低温低压缺氧环境对血清甲状腺素的影响  

Effects of hypothermia and hypoxia on blood serum thyroxin level

作　　者：梅丹[1] 孙奎[1] 徐斌[1] 王丽华[1] 金连海[1] 

机构地区：[1]空军医学高等专科学校,吉林市132013

出　　处：《空军医高专学报》1998年第4期200-203,共4页

基　　金：全军"95"医药卫生重点课题(A-17)

摘　　要：为探讨低温低压缺氧环境对动物甲状腺素分泌的影响,笔者检测了环境温度为10℃时,低压舱模拟上升至3.0、5.Okm高度停留1h,大鼠血清三碘甲腺氨酸（T_3）、四碘甲腺原氨酸（T_4）和促甲状腺素（TSH）含量的变化,同时也检测了血清葡萄糖（GS）、胆固醇（CH）、甘油三脂（TG）和肌酐水平。结果显示,在10℃低温条件下,TSH先下降后升高（P<0.01）,甲状腺素分泌显著降低（P<0.01）;5.0km高度时大鼠血清GS、CH和TG显著升高（P<0.01）,肌酐含量则显著下降（P<0.01）。表明在低温条件下,随着低压缺氧程度的加深,体内甲状腺素分泌减少,物质代谢降低。To explore the effects of hypoxia at hypothermia and low pressure on blood serum thydroxin level, triiodothyronine (T3), tetraiodothyronine (T4) and thy-rotropic hormone (TSH) were determined as well as glucose (GS), cholesterol (CH), creatinine in blood serum. The results indicated that at the height of 3 km, T3, T4 decreased (P < 0.01) and TSH decreased (P < 0.01) at first and then increased; at the height of 5 km, GS, CH and TG increased signifcantly (P<0.01) while creatinine decreased rernarkedly (P<0.01). It was shown that at low temperature the thyroxin level and metabolism lowered as the pressure lowered and hypoxia increased.

关 键 词：低温 缺氧 甲状腺素 

分 类 号：R363[医药卫生—病理学]