住院精神病人脑电异常率及其相关因素研究  

A CORRELATING STUDY OF BRAIN ELECTRLCAL ACTIVITY OF PSYCHOTIC IN PATIENTS AND THEIR CLINICAL FEATRUES

作　　者：王继军[1] 张明岛[1] 陈兴时[1] 楼翡璎[1] 梁建华[1] 徐巍[1] 李春波[2] 

机构地区：[1]上海市精神卫生研究所 [2]上海第二医科大学精神医学教研室

出　　处：《现代电生理学杂志》1997年第2期73-76,共4页Journal of Modern Electrophysiology

摘　　要：本研究自行设计统一调查表,收集到168例住院精神病人的一般临床资料和脑电地形图(Brain electrical activity mapping,BEAM)和脑诱发电位(Brain cvoked potentials,BEP)检查报告结果,并应用SPSS统计软件分析处理结果。结果如下:1.住院精神病人BEAM、BEP异常率以器质性精神障碍最高(76.92％),重性精神病居次(精神分裂症45.53％,躁狂症57.14％,抑郁症50.0％),轻性精神障碍(包括神经症或其它与文化相关综合征)最低(23.08％)。脑电异常率高低与疾病性质、病情严重程度相关,与临床印象吻合;2.精神分裂症患者的脑电异常率又受治疗手段的影响,ECT治疗和氯氮平治疗均使患者BEAM异常率增高(P<0.01);接受氯氮平治疗者,BEP异常率见低(P<0.01),另外,BEP异常与疗效也存在一定的相关性(P<0.05),疗效好者,BEP异常率低。 本研究还发现BEAM与BEP检查结果缺乏很好的一致性,两者反映的临床特点有差异。作为临床常规检查,两者可以相辅相成,更好地协助临床诊断和疗效监测工作。The incidences of abnormal BEAM (Brain electrical activity mapping) and /or BEP (Brain evoked potentials) were investigated among 168 psychotic inpatients.The results showed that the incidence was predominantly related with the nature of the psychosis (P<0.05) and no consistency was found between the results of these 2 kinds of brain electrical activity tests (P>0.05).As for 123 schizophrenics,a logistic regression analysis revealed that ECT (electric convulsive therapy) or clozapine treatment was correlated with the abnormal BEAM (P<0.01),and bad treatment efficiency was correlated with the abnormal BEP (P<0.05).

关 键 词：脑电地形图 脑诱发电位 精神病人 精神分裂症病人 

分 类 号：R749[医药卫生—神经病学与精神病学]