宁夏枸杞对CCl_4诱发鼠肝脂质过氧化损伤的保护作用  

Study of the protective effect of Lycium barbarum L.(LbL) on lipid peroxidation injury of rat liver induced by CCl 4./

作　　者：沈泳[1] 苏利民[1] 杨卫东[1] 任彬彬[1] 李国莉[1] 刘秀芳[1] 

机构地区：[1]宁夏医学院

出　　处：《中国食品卫生杂志》1997年第3期3-4,50,共3页Chinese Journal of Food Hygiene

基　　金：国家自然科学基金

摘　　要：为观察宁夏枸杞（ＬｂＬ）对大鼠肝脏的影响，用四氯化碳（ＣＣｌ４）诱发大鼠肝脂质过氧化。结果ＬｂＬ在高剂量（０．７ｇ／１００ｇＢＷ）及低剂量（０．３５ｇ／１００ｇＢＷ）均能明显降低肝脏中丙二醛含量并提高超氧化物歧化酶（ＳＯＤ）的活性。提示ＬｂＬ能减轻生物体内脂质过氧化损伤，其保肝作用的机理是减少自由基的产生。Lipid peroxidation was induced in wistar rat liver by carben tetrachloride (CCl 4) for studying the effect of LbL on the liver. The results showed the malonic dialdehyde content was reduced and the activity of superoxide dismutase (SOD) was increased by LbL at both concentration of 0.7g/100g BW and 0.35g/100g BW. It indicated the mechanism of LbL protecting the rat liver from the lipid peroxidation injury was related to reduced the free radical. Author's address Shen Yong,Dept. of Preventive Medcine, the Ningxia Hui Autonomous Region Medical College, Yinchuan 750004, PRC.

关 键 词：宁夏枸杞 抗氧化 脂质过氧化 超氧化物歧化酶 自由基 四氯化碳 大鼠 肝脏 

分 类 号：R-332[医药卫生]