长期存活与转移肾癌间质肥大细胞、淋巴细胞反应的研究  

Studies on Mast Cells and Lymphocytes in the Stroma of Renal Cell Carcinoma in the Cases of Long-termSurvival and Metastasized after Operation

作　　者：张冠军[1] 张学斌[1] 南勋义[2] 陈兴发[2] 

机构地区：[1]西安医科大学第一临床医学院病理科,西安710061 [2]西安医科大学第一临床医学院泌尿外科,西安710061

出　　处：《现代泌尿外科杂志》1996年第1期51-52,34,共3页Journal of Modern Urology

摘　　要：对41例长期存活与短期转移肾癌间质中肥大细胞、淋巴细胞反应进行定量观察及相互关系研究。结果发现:长期存活肾癌交界区及中心区肥大细胞计数均明显高于短期转移者(P<0.01),且交界区肥大细胞计数高于中心区。长期存活肾癌间质淋巴细胞反应程度也比短期转移者强(P<0.01)。其反应程序与肥大细胞计数有明显相关性。二者反应强者,患者生存期长、预后好。提示观察肾癌问质肥大细胞、淋巴细胞反应可为临床判断其恶性度及预后提供较为可靠的量化指标。The mast cells and Lymphocytes reaction in the stroma of 41 cases of renal cell carcinoma were observed quantitatively. It was found that the amount of mast cells in the margin and central zone of carcinoma, and the degree of lymphocyte reaction was respectively more and obvious in the long-term survival cases than that in the metastasized one. A positive correlation was observed between the amount of mast cells and the degree of Lymphocyte reaction. These suggest that quantitative analysis of mast cells and lymphocyte in the stroma of renal cell carcinoma might be a valuable method for clinical evaluating its prognosis.

关 键 词：肾癌 肥大细胞 淋巴细胞 预后 

分 类 号：R737.11[医药卫生—肿瘤]