肾细胞癌50例术后放疗分析  

POSTOPERATIVE RADIOTHERAPY OF 50 PATIENTS WITH RENAL CELL CARCINOMA

作　　者：王庆国[1] 李庆琪[1] 

机构地区：[1]北京医科大学第一医院放疗科,100034

出　　处：《中华放射肿瘤学杂志》1995年第4期32-34,67-68,共5页Chinese Journal of Radiation Oncology

摘　　要：1977年～ 1990年共收治肾细胞癌术后放疗病人 5 0例 ,其 3,5 ,10年生存率分别为 6 0 .0 %、5 1.1%和 31.8%。 5年生存率 : ～ 期为 6 9.2 % , ～ 期为 4 3.8% ,与单纯手术相比术后放疗可提高患者 5年生存率。放疗应注意保护重要脏器 ,注意时间、剂量、分次设计 ,以免发生严重放疗并发症。区域淋巴结转移、肾周围器官侵犯和肾或腔静脉癌栓是预后不良因素 ,尤以前二者更为明显。本组病例83.3%死于远地转移 ,肺转移最多见占 5 8.3% ,其次是骨转移占 2 5 .6 % ,提示需寻找新的综合治疗方案解决远地转移问题。From 1977 to 1990, 50 patients with renal cell carcinoma were given postoperative radiotherapy. The 3-,5- and 10-year survival rates were 60.0%,51.5% and 31.8%. The 5-year survival rate of StageⅠ～Ⅱ lesions was 69.2% and that of stageⅢ～Ⅳ lesions was 43.8%, which are better than those treated by surgery alone. Regional lymphatic metastasis, invasion of the nearby organs and vena caval cancerous thrombosis were the ominous signs, especially the former two. 83.3% of the patients died of distant metastasis. Lung was most common(58.3%)and then, bone metastasis (25.6%). The authors believe newer combination therapy against distant metastasis is needed to improve the results.

关 键 词：肾细胞癌 术后放疗 预后 

分 类 号：R737.11[医药卫生—肿瘤]